Results 61 to 70 of about 287,989 (277)

Topology optimization of multiphase material structures under design dependent pressure loads [PDF]

open access: yesInternational Journal for Simulation and Multidisciplinary Design Optimization, 2009
In this paper, design-dependent pressure loads are addressed for topology optimization problems of multiphase material structures. The modeling of unidirectional load distribution with respect to the material density is studied and mathematical ...
Gao Tong, Zhang Wei-hong
doaj   +1 more source

Influence of Load Modeling on the Cost of Ensuring Stability Using TSCOPF

open access: yesIEEE Access, 2023
Load modeling significantly impacts the time-domain response of power systems in transient stability studies but this effect is often underestimated in Transient Stability Constrained Optimal Power flow (TSCOPF) studies.
Francisco Arredondo   +4 more
doaj   +1 more source

Shear stress fluctuations in the granular liquid and solid phases

open access: yes, 2005
We report on experimentally observed shear stress fluctuations in both granular solid and fluid states, showing that they are non-Gaussian at low shear rates, reflecting the predominance of correlated structures (force chains) in the solidlike phase ...
A. Petri   +14 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Use of cohesive elements in fatigue analysis [PDF]

open access: yes, 2008
Cohesive laws describe the resistance to incipient separation of material surfaces. A cohesive finite element is formulated on the basis of a particular cohesive law.
Black, T. M.   +2 more
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Regression-SARIMA modelling of daily peak electricity demand in South Africa

open access: yesJournal of Energy in Southern Africa, 2017
In this paper, seasonal autoregressive integrated moving average (SARIMA) and regression with SARIMA errors (regression-SARIMA) models are developed to predict daily peak electricity demand in South Africa using data for the period 1996 to 2009.
Delson Chikobvu, Caston Sigauke
doaj   +1 more source

Transformation of load-settlement curve based on load transfer at pile-soil interface

open access: yesYantu gongcheng xuebao, 2021
The self-anchoring test is a new method to detect the bearing capacity of pile foundation.The indoor model tests and the numerical simulation are used to explore the difference of the Q-S curves between the static load tests and the self-anchoring tests,
MA Wen-jie 1, 2, WANG Xu 3, WANG Bing-long 1, 2, WANG Bo-lin 3
doaj   +1 more source

A fixed-point approximation for a routing model in equilibrium [PDF]

open access: yes, 2013
We use a method of Luczak (arXiv:1212.3231) to investigate the equilibrium distribution of a dynamic routing model on a network. In this model, there are $n$ nodes, each pair joined by a link of capacity $C$. For each pair of nodes, calls arrive for this
Graham Brightwell, J. Luczak, Malwina
core  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

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