Results 51 to 60 of about 3,504,804 (362)

Asymptotical stability analysis of conformable fractional systems

Journal of Taibah University for Science, 2020
In this paper, we analyses the asymptotical stability of the system in the form ${T_\alpha }y(\tau ){ = A}y(\tau ) + f(\tau ,y(\tau )) $ with the initial value $y({\tau _0}) = {y_0} $.
Yongfang Qi, Xuhuan Wang
doaj   +1 more source

Dynamics of the Exponential Population Growth System with Mixed Fractional Brownian Motion

Complexity, 2021
This paper examines the dynamics of the exponential population growth system with mixed fractional Brownian motion. First, we establish some useful lemmas that provide powerful tools for studying the stochastic differential equations with mixed ...
Weijun Ma, Wei Liu, Quanxin Zhu, Kaibo Shi   +3 more
doaj   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

FEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

A stepwise emergence of evolution in the RNA world

FEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Exponential and sub-exponential stability times for the NLS on the circle

Rendiconti Lincei, Matematica e Applicazioni, 2019
In this note we study stability times for a family of parameter dependent nonlinear Schrödinger equations on the circle, close to the origin. Imposing a suitable Diophantine condition (first introduced by Bourgain), we state a rather flexible Birkho¤ Normal Form theorem, which implies, e.g., exponential and sub-exponential time estimates in the Sobolev
Biasco, L., Massetti, J. E., Procesi, M.
openaire   +5 more sources

In vivo evidence for glycyl radical insertion into a catalytically inactive variant of pyruvate formate‐lyase

FEBS Letters, EarlyView.
Dimeric pyruvate formate‐lyase cleaves pyruvate using a radical‐based mechanism. G734 serves as a radical storage location, and the radical is transferred to the catalytic C419 residue. Mutation of the C418‐C419 pair causes loss of enzyme activity, but does not impede radical introduction onto G734. Therefore, cis‐ but not trans‐radical transfer occurs
Michelle Kammel, A. F. Volker Wagner, R. Gary Sawers   +2 more
wiley   +1 more source

Exponential stability analysis for nonlinear time-varying perturbed systems on time scales

AIMS Mathematics, 2023
This paper is concerned with the stability of nonlinear time-varying perturbed system on time scales under the assumption that the corresponding linear time-varying nominal system is uniformly exponentially stable.
Cheng-Xiu Qiang , Jian-Ping Sun , Ya-Hong Zhao   +2 more
doaj   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

Landscape of BRAF transcript variants in human cancer

Molecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda, Danilo Tatoni, Gianluca Mattei, Alberto Magi, Romina D'Aurizio, Laura Poliseno   +5 more
wiley   +1 more source

New Conditions for the Exponential Stability of Pseudolinear Difference Equations in Banach Spaces

Abstract and Applied Analysis, 2016
We study the local exponential stability of evolution difference systems with slowly varying coefficients and nonlinear perturbations. We establish the robustness of the exponential stability in infinite-dimensional Banach spaces, in the sense that the ...
Rigoberto Medina
doaj   +1 more source