Results 51 to 60 of about 276,545 (338)

Unconventional mRNA processing and degradation pathways for the polycistronic yrzI (spyTA) mRNA in Bacillus subtilis

open access: yesFEBS Letters, EarlyView.
The S1025 peptide is the major antidote to the YrzI toxin, which we renamed here as SpyT (Small Peptide YrzI Toxin) and SpyA (Small Peptide YrzI Antitoxin) (1). Degradation of the toxin–antitoxin spyTA mRNA, either by a translation‐dependent cleavage by the endoribonuclease Rae1 (2) or by direct attack by 3′‐exoribonucleases (3), also contributes to ...
Laetitia Gilet   +4 more
wiley   +1 more source

Exponential stability analysis for nonlinear time-varying perturbed systems on time scales

open access: yesAIMS Mathematics, 2023
This paper is concerned with the stability of nonlinear time-varying perturbed system on time scales under the assumption that the corresponding linear time-varying nominal system is uniformly exponentially stable.
Cheng-Xiu Qiang   +2 more
doaj   +1 more source

Exponential and sub-exponential stability times for the NLS on the circle

open access: yesRendiconti Lincei, Matematica e Applicazioni, 2019
In this note we study stability times for a family of parameter dependent nonlinear Schrödinger equations on the circle, close to the origin. Imposing a suitable Diophantine condition (first introduced by Bourgain), we state a rather flexible Birkho¤ Normal Form theorem, which implies, e.g., exponential and sub-exponential time estimates in the Sobolev
Biasco, L., Massetti, J. E., Procesi, M.
openaire   +4 more sources

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

open access: yesMolecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi   +6 more
wiley   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini   +10 more
wiley   +1 more source

Stability of hybrid pantograph stochastic functional differential equations [PDF]

open access: yesarXiv, 2021
In this paper, we study a new type of stochastic functional differential equations which is called hybrid pantograph stochastic functional differential equations. We investigate several moment properties and sample properties of the solutions to the equations by using the method of multiple Lyapunov functions, such as the moment exponential stability ...
arxiv  

Comparative study of adenosine 3′‐pyrophosphokinase domains of MuF polymorphic toxins

open access: yesFEBS Open Bio, EarlyView.
With the ultimate goal of understanding the association of toxin‐immunity modules to temperate phages, we characterized toxins from three prophages and examined cross‐protection from immunity proteins. The toxins exhibit adenosine 3′‐pyrophosphokinase activity and are toxic in Escherichia coli.
Eloïse M. Paulet   +6 more
wiley   +1 more source

New Conditions for the Exponential Stability of Pseudolinear Difference Equations in Banach Spaces

open access: yesAbstract and Applied Analysis, 2016
We study the local exponential stability of evolution difference systems with slowly varying coefficients and nonlinear perturbations. We establish the robustness of the exponential stability in infinite-dimensional Banach spaces, in the sense that the ...
Rigoberto Medina
doaj   +1 more source

KCS1 and VIP1, the genes encoding yeast phosphoinositol pyrophosphate synthases, are required for Ca2+‐mediated response to dimethylsulfoxide (DMSO)

open access: yesFEBS Open Bio, EarlyView.
Ca2+‐mediated response to DMSO was investigated in Saccharomyces cerevisiae cells expressing Ca2+‐dependent aequorin. Cell exposure to DMSO induced a cytosolic Ca2+ wave dependent on the integrity of the Cch1/Mid1 channel. Deletion of KCS1 or VIP1 genes encoding the phosphoinositol pyrophosphate (PP‐IP) synthases suppressed the DMSO‐induced Ca2 ...
Larisa Ioana Gogianu   +4 more
wiley   +1 more source

Exponential stability analysis for a class of switched nonlinear time-varying functional differential systems [PDF]

open access: yesarXiv, 2021
This paper proposes a unified approach for studying global exponential stability of a general class of switched systems described by time-varying nonlinear functional differential equations. Some new delay-independent criteria of global exponential stability are established for this class of systems under arbitrary switching which satisfies some ...
arxiv  

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