Results 61 to 70 of about 12,477,982 (369)

The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum

open access: yesFEBS Letters, EarlyView.
In Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Foteini Karapanagioti   +3 more
wiley   +1 more source

Nikolskii Type Inequalities for Entire Functions of Exponential Type in Lorentz Zygmund Spaces [PDF]

open access: yesarXiv, 2021
Nikolskii type inequalities for entire functions of exponential type on Rn for the Lorentz Zygmund spaces are obtained. Some new limiting cases are examined. Application to Besov type spaces of logarithmic smoothness is given.
arxiv  

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

open access: yesMolecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi   +6 more
wiley   +1 more source

Generalized Semi Exponential Type Estimator under Systematic Sampling

open access: yesJournal of Statistical Theory and Applications (JSTA), 2018
In sample surveys, collection of auxiliary information together with the main variable of interest is very important to increase the efficiency of the estimators of population parameters of interest.
Muhammad Nouman Qureshi   +2 more
doaj   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini   +10 more
wiley   +1 more source

Multivalence of bivariate functions of bounded index

open access: yesLe Matematiche, 2015
This paper examines the relationship between the concept of bounded index and the radius of equivalence, respectively p-valence, of entire bivariate functions and their partial derivatives at arbitrary points in C^2.
Fatih Nuray, Richard F. Patterson
doaj  

Eigenvalue Problems for Exponential-Type Kernels

open access: yesComput. Methods Appl. Math., 2019
We study approximations of eigenvalue problems for integral operators associated with kernel functions of exponential type. We show convergence rate | λ k - λ k , h | ≤ C k ⁢ h 2 {\lvert\lambda_{k}-\lambda_{k,h}\rvert\leq C_{k}h^{2}} in the case of ...
Difeng Cai, P. Vassilevski
semanticscholar   +1 more source

Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?

open access: yesMolecular Oncology, EarlyView.
Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley   +1 more source

A study of thermodynamic properties of quadratic exponential-type potential in D-dimensions

open access: yesRevista mexicana de física, 2018
We solved the Schrodinger equation with Quadratic Exponential-Type Potential (QEP) model in D-dimensions using the Modified factorization method. The energy eigenvalues and total wavefunctions were obtained in a Gauss hypergeometric form.
U. Okorie   +3 more
semanticscholar   +1 more source

Comparative study of adenosine 3′‐pyrophosphokinase domains of MuF polymorphic toxins

open access: yesFEBS Open Bio, EarlyView.
With the ultimate goal of understanding the association of toxin‐immunity modules to temperate phages, we characterized toxins from three prophages and examined cross‐protection from immunity proteins. The toxins exhibit adenosine 3′‐pyrophosphokinase activity and are toxic in Escherichia coli.
Eloïse M. Paulet   +6 more
wiley   +1 more source

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