Results 61 to 70 of about 1,512,653 (346)

Sensitivity function and entropy increase rates for z-logistic map family at the edge of chaos

open access: yes, 2006
It is well known that, for chaotic systems, the production of relevant entropy (Boltzmann-Gibbs) is always linear and the system has strong (exponential) sensitivity to initial conditions.
Abe   +14 more
core   +2 more sources

Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?

open access: yesMolecular Oncology, EarlyView.
Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley   +1 more source

The role of forward self-similar solutions in the Cauchy problem for semi-linear heat equations with exponential nonlinearity [PDF]

open access: yesarXiv, 2021
We consider the Cauchy problem for semi-linear heat equations with exponential nonlinearity. The main purpose of this paper is to prove the existence of solutions lying on the borderline between global existence and blow-up infinite time. The existence has been shown for semi-linear heat equations with power type nonlinearity.
arxiv  

Landscape of BRAF transcript variants in human cancer

open access: yesMolecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda   +5 more
wiley   +1 more source

On Lojasiewicz-type inequalities for exponential polynomials [PDF]

open access: yesJournal of Mathematical Analysis and Applications, 1988
AbstractLet f(z) = ∑Nn-1 fn(z) eiαnz be an exponential polynomial, that is, the coefficients fn(z) are polynomials in one complex variable. We discuss the question of how close distinct roots of the equation f(z) = 0 can get to each other.
Carlos A. Berenstein, A. Yger, A. Yger
openaire   +1 more source

Exponential stability of stochastic Hopfield neural network with mixed multiple delays

open access: yesAIMS Mathematics, 2021
This paper investigates the problem for exponential stability of stochastic Hopfield neural networks involving multiple discrete time-varying delays and multiple distributed time-varying delays.
Qinghua Zhou   +3 more
doaj   +1 more source

On Order Statistics for GS-Distributions [PDF]

open access: yes, 2012
In this article, a class of distributions is used to establish several recurrence relations satisfied by single and product moments of order statistics and progressive Type-II right censoring.
Amein, M. M.   +2 more
core   +1 more source

Comparative study of adenosine 3′‐pyrophosphokinase domains of MuF polymorphic toxins

open access: yesFEBS Open Bio, EarlyView.
With the ultimate goal of understanding the association of toxin‐immunity modules to temperate phages, we characterized toxins from three prophages and examined cross‐protection from immunity proteins. The toxins exhibit adenosine 3′‐pyrophosphokinase activity and are toxic in Escherichia coli.
Eloïse M. Paulet   +6 more
wiley   +1 more source

KCS1 and VIP1, the genes encoding yeast phosphoinositol pyrophosphate synthases, are required for Ca2+‐mediated response to dimethylsulfoxide (DMSO)

open access: yesFEBS Open Bio, EarlyView.
Ca2+‐mediated response to DMSO was investigated in Saccharomyces cerevisiae cells expressing Ca2+‐dependent aequorin. Cell exposure to DMSO induced a cytosolic Ca2+ wave dependent on the integrity of the Cch1/Mid1 channel. Deletion of KCS1 or VIP1 genes encoding the phosphoinositol pyrophosphate (PP‐IP) synthases suppressed the DMSO‐induced Ca2 ...
Larisa Ioana Gogianu   +4 more
wiley   +1 more source

The Brownian traveller on manifolds [PDF]

open access: yes, 2011
We study the influence of the intrinsic curvature on the large time behaviour of the heat equation in a tubular neighbourhood of an unbounded geodesic in a two-dimensional Riemannian manifold.
Kolb, Martin, Krejcirik, David
core  

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