Results 61 to 70 of about 89,992 (292)

Logic‐Gated HSV‐TK/GCV Suicide Gene Circuit for Triple‐Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
The BRAS comprises two modular genetic components driven by distinct tumor‐specific promoters and a failsafe layer with the NOT gate. This multi‐input logic gate circuit enables precise, specific expression of HSV‐TK in breast cancer cells with hardly expression in normal cell and effectively inhibits tumor growth in a triple‐negative breast cancer ...
Shasha Tang   +10 more
wiley   +1 more source

Iterative Estimation of Solutions to Noisy Nonlinear Operator Equations in Nonparametric Instrumental Regression

open access: yes, 2013
This paper discusses the solution of nonlinear integral equations with noisy integral kernels as they appear in nonparametric instrumental regression. We propose a regularized Newton-type iteration and establish convergence and convergence rate results ...
Dunker, Fabian   +4 more
core   +2 more sources

In Situ Characterisation of Hydrogels via Dynamic Interface Printing

open access: yesAdvanced Science, EarlyView.
ABSTRACT Hydrogels have become pivotal materials for tissue engineering, robotics, biomedical devices, and sensing applications due to their diverse material compositions and tunable mechanical properties. While significant effort has focused on developing novel manufacturing approaches such as extrusion bioprinting and light‐based fabrication methods,
Callum Vidler   +2 more
wiley   +1 more source

Photon‐Sphere Modes in Curved Optical Microcavities: A Black‐Hole Analogue Laser

open access: yesAdvanced Science, EarlyView.
An optical analogue of a Schwarzschild black hole is realized using curved microcavities that preserve light‐like geodesics. A new family of laser modes confined around the photon sphere is identified alongside conventional whispering‐gallery modes. Analytical theory, numerical simulations, and experiments reveal curvature‐induced confinement, enabling
Chenni Xu   +9 more
wiley   +1 more source

Stability Analysis of Switched System With All Subsystems Unstable Under Novel Average Dwell Time Criteria

open access: yesIEEE Access, 2019
This paper analyzes the stability problem of continuous-time switched systems with all subsystems unstable. With each switched system having a minimum dwell time, this paper considered that the Lyapunov function converges in the minimum dwell time and ...
Xiaozeng Xu, Xiang Mao, Hongbin Zhang
doaj   +1 more source

Volume-Preserving flow by powers of the mth mean curvature in the hyperbolic space [PDF]

open access: yes, 2013
This paper concerns closed hypersurfaces of dimension $n(\geq 2)$ in the hyperbolic space ${\mathbb{H}}_{\kappa}^{n+1}$ of constant sectional curvature $\kappa$ evolving in direction of its normal vector, where the speed is given by a power $\beta (\geq ...
Guo, Shunzi, Li, Guanghan, Wu, Chuanxi
core  

Sylvester's question and the Random Acceleration Process

open access: yes, 2008
Let n points be chosen randomly and independently in the unit disk. "Sylvester's question" concerns the probability p_n that they are the vertices of a convex n-sided polygon. Here we establish the link with another problem. We show that for large n this
Burkhardt T W   +8 more
core   +1 more source

Neural Fields for Highly Accelerated 2D Cine Phase Contrast MRI

open access: yesAdvanced Science, EarlyView.
ABSTRACT 2D cine phase contrast (CPC) MRI provides quantitative information on blood velocity and flow within the human vasculature. However, data acquisition is time‐consuming, motivating the reconstruction of the velocity field from undersampled measurements to reduce scan times. In this work, neural fields are proposed as a continuous spatiotemporal
Pablo Arratia   +7 more
wiley   +1 more source

Factorization-Based Active Contour for Water-Land SAR Image Segmentation via the Fusion of Features

open access: yesIEEE Access, 2019
The segmentation of synthetic aperture radar (SAR) water-land images is a very difficult task not only because of strong multiplicative noise but also due to the blurred boundary, irregular shape, and together with diminished contrast.
Qingxia Meng   +3 more
doaj   +1 more source

Identifying and attacking the saddle point problem in high-dimensional non-convex optimization [PDF]

open access: yes, 2014
A central challenge to many fields of science and engineering involves minimizing non-convex error functions over continuous, high dimensional spaces.
Caglar Gulcehre   +6 more
core  

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