Results 51 to 60 of about 913,446 (310)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

The Relationship of the Region’s Export Potential and the Start-Up Movement of the Youth [PDF]

open access: yesЭкономика региона, 2018
Enhancing the role of entrepreneurship as an instrument of export diversification for sustainable development of the economy of the country and regions is a topical problem.
Pavel Leonidovich Glukhikh   +3 more
doaj   +1 more source

Management of labour productivity at the enterprises of the agricultural industry of Ukraine

open access: yesМенеджмент та підприємництво: тренди розвитку, 2021
The agro-industrial complex is one of the main budget-forming sectors of the national economy of Ukraine; agribusiness opens up prospects for leadership for our state in the world market. Therefore, an important step for unlocking the export potential of
Liudmyla Bukharina   +2 more
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Competitiveness of Pakistani rice in international market and export potential with global world: A panel gravity approach

open access: yesCogent Economics & Finance, 2018
Rice is an important source for foreign exchange earnings for Pakistan’s economy, keeping this fact in mind, this study is to calculate competitiveness of rice export of Pakistan in international market compared to largest exporter countries and this ...
Muhammad Saqib Irshad   +2 more
doaj   +1 more source

Digitalization of Trade as a Factor of Development of Export Potential of the Republic of Belarus

open access: yesЦифровая трансформация, 2020
The purpose of the article is to show how the digitalization of trade can lead to the development of the export potential of the Republic of Belarus. The article discloses theoretical approaches to digitalization of trade as a combination of traditional ...
N. V. Yurova
doaj   +1 more source

Export potential of the Altai territory

open access: yesGrand Altai Research & Education / Наука и образование Большого Алтая, 2021
В статье показан экспортный потенциал Алтайского края, обоснованы тенденции развития экспорта продукции региона, в том числе АПК, приоритеты развития регионального экспорта агропромышленной продукции на основе ресурсного потенциала и возможностей региона.
openaire   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

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