Results 111 to 120 of about 7,001,402 (299)

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Landslide exposure analysis by utilizing big geodata in Bogor area, West Java Province of Indonesia [PDF]

Journal of the Bulgarian Geographical Society
Landslide exposure is an adept approach to measuring the consequences of a landslide hazard on elements at risk. Landslides in the Bogor area, Province of West Java, Indonesia, have increased in number and consequences since 2015. The Bogor area also has
Astisiasari Astisiasari, Wisyanto Wisyanto, Dian Melati, Sukristiyanti Sukristiyanti, Raditya Umbara, Yukni Arifianti, Trinugroho Trinugroho, Lian Andikasari, Taufik Ramdhani   +8 more
doaj   +3 more sources

Segmental hair mercury evaluation of a single family along the Upper Madeira Basin, Brazilian Amazon

Cadernos de Saúde Pública
Mercury pollution (MeHg) up the aquatic food chains in the Amazonian ecosystems has been a major concern in environmental health. Riverside people (ribeirinhos) along the Upper Madeira river are heavy fish eaters.
Ana Amélia Peixoto Boischio, Elsa Cernichiari, Diane Henshel   +2 more
doaj  

Histomorphometric Analysis of Sun-exposed and Nonsun-exposed Sites of Skin among North Indian Female Population

National Journal of Clinical Anatomy
Background: Knowing the normal values of different layers of skin is important, especially for esthetic and plastic surgeons in skin transfer operations, skin-related disorders, and their clinical investigations in drugs and vaccine research.
Anjali Sharan, Jolly Agarwal, Mahendra Kumar Pant, Swati Saxena, Rajesh Kumar Maurya, Abhinav Kumar, Anisha Nautiyal, Deepika Sharma   +7 more
doaj   +1 more source

Lung cancer screening an asbestos exposed population: Existing lung cancer risk criteria are not sufficient. [PDF]

Respirology, 2023
Brims FJH, Harris EJA, Murray C, Kumarasamy C, Ho A, Adler B, Franklin P, de Klerk NH.   +7 more
europepmc   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

B-Cell Epitope Mapping of the Plasmodium falciparum Malaria Vaccine Candidate GMZ2.6c in a Naturally Exposed Population of the Brazilian Amazon. [PDF]

Vaccines (Basel), 2023
Baptista BO, Souza ABL, Oliveira LS, Souza HADS, Barros JP, Queiroz LT, Souza RM, Amoah LE, Singh SK, Singh SK, Theisen M, Rodrigues-da-Silva RN, Riccio EKP, Totino PRR, Lima-Junior JDC, Daniel-Ribeiro CT, Pratt-Riccio LR.   +16 more
europepmc   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Effects of Polybrominated Diphenyl Ethers on Hormonal and Reproductive Health in E-Waste-Exposed Population: A Systematic Review. [PDF]

Int J Environ Res Public Health, 2022
Singh V, Cortes-Ramirez J, Toms LM, Sooriyagoda T, Karatela S.   +4 more
europepmc   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source