Results 151 to 160 of about 8,026,862 (350)

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Impact of short-term exposure to ambient air pollution on cardiovascular disease outpatient visits: a time-series study in Yichang, China [PDF]

Wenhan Wang, Xiaoyan Ming, Lu Chen, Yingdong Chen, Zhongcheng Yang, Chi Hu, Qiuju Zhang   +6 more
openalex   +1 more source

Barometer Exposure [PDF]

Science, 1887
openaire   +2 more sources

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

The Correlation between Occupational Pesticide Exposure with The Incidence of COPD and Chronic Bronchitis: a Systematic Review and Meta-Analysis

Safety and Health at Work, 2022
Achmad Ilham Tohari, Muhammad Yuda Nugraha, Muhammad Rijal Fahrudin Hidayat, Bagus Wahyu Mulyono, Tegar Syaiful Qodar, Elly Nurus Sakinah, Supangat Supangat, Peter Lundqvist   +7 more
doaj   +1 more source

The metabolic impact of hypoxia exposure in human obesity [PDF]

, 2021
Laurentius Johannes van Meijel
openalex   +1 more source

PAH Exposure

Environmental Health Perspectives, 2009
Fowler, Paul A., O’Shaughnessy, Peter J., Rhind, Stewart M., Ayres, Jon   +3 more
openaire   +2 more sources

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Early life exposure to triclosan from antimicrobial daily necessities may increase the potential risk of autism spectrum disorder: A multicenter study in China

, 2022
Qionghui Wu, Ting Yang, Li Chen, Ying Dai, Hua Wei, Feiyong Jia, Yan Hao, Ling Li, Jie Zhang, Lijie Wu, Xiaoyan Ke, Mingji Yi, Qi Hong, Jinjin Chen, Shuanfeng Fang, Yichao Wang, Qi Wang, Chunhua Jin, Ronggui Hu, Jie Chen, Tingyu Li   +20 more
openalex   +1 more source

Joint effects of prenatal household air pollution exposure from multiple sources on preterm birth - A case-control study with propensity score matching [PDF]

, 2022
Xin-Chen Liu, Esben Strodl, Weikang Yang, Lihua Huang, Xiaona Yin, Guo‐Min Wen, Deng‐Li Sun, Dan‐Xia Xian, Bingjie Hu, Weiqing Chen   +9 more
openalex   +1 more source