Results 191 to 200 of about 4,930,320 (325)

Multicompartmental analysis of microbiome alterations under radiation stress. [PDF]

AMB Express
Mukhanbetzhanov N, Zhetkenev S, Vinogradova E, Sergazy S, Jarmukhanov Z, Issilbayeva A, Kossumov A, Kassenova A, Mukhametuly B, Kenessarin M, Zhumadilov K, Stepanenko V, Bogacheva V, Petukhov A, Sato H, Endo S, Fujimoto N, Hoshi M.   +17 more
europepmc   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Gut Microbial Diversity in Antibiotic-Naive Children After Systemic Antibiotic Exposure: A Randomized Controlled Trial

Clinical Infectious Diseases, 2017
T. Doan, A. Arzika, Kathryn J. Ray, S. Cotter, Jessica Kim, R. Maliki, Lina Zhong, Zhaoxia Zhou, T. Porco, Benjamin Vanderschelden, J. Keenan, T. Lietman   +11 more
semanticscholar   +1 more source

Antibiotic exposure exacerbates acute-on-chronic liver failure via gut microbiota imbalance and secondary liver lesion. [PDF]

J Med Microbiol
Yang S, Wang J, Yang N, Li J, Jin L, Zhang Y, Wang H, Fu J, Chen T, Zhao Y, He Y.   +10 more
europepmc   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

Multilevel analysis of prevalence and associated factors of minimum dietary diversity among children 6-23 months in Somaliland: evidence from Somaliland demographic and health survey (2020). [PDF]

Ital J Pediatr
Osman OM, Abdi HA, Nuh AM, Ali HA, Muse AH, Osman AM.   +5 more
europepmc   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Dietary intake of enrofloxacin promotes the spread of antibiotic resistance from food to simulated human gut. [PDF]

ISME J
Wang Q, Liu C, Sun Y, Li X, Gu W, Wang N, Sun S, Luo Y.   +7 more
europepmc   +1 more source