Results 51 to 60 of about 10,673 (169)

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

THE COMPARATIVE ANALYSIS OF THE POPULATION MEDICAL EXPOSURE IN RUSSIAN FEDERATION AND TATARSTAN REPUBLIC FOR THE PERIOD 2002-2006

open access: yesРадиационная гигиена, 2017
The conducted comparative analysis of the medical exposure of the population of Russian Federation and one of its administrative territories reveals the leading importance for the medical exposure reduction of the renewing of X-ray equipment and the ...
V. G. Morozov   +2 more
doaj  

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Dose patterns in commercially insured subjects chronically exposed to opioids: a large cohort study in the United States

open access: yesBMC Palliative Care, 2010
Background Little data exist on how opioid doses vary with the length of exposure among chronic opioid users. Methods To characterize the change in the dosage of opioids over time, a retrospective cohort study using the PharMetrics database for the years
Boston Raymond   +5 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Medical diagnostic exposure in the Russian Federation: regulatory problems and proposals for their solution

open access: yesРадиационная гигиена
The analysis of trends in levels of radiation exposure of the public in the Russian Federation in recent years indicates a steady increase in patient doses from medical exposure.
A. V. Vodovatov   +4 more
doaj   +1 more source

The head of invasive cardiologists as a target of professional exposure to ionizing radiation [PDF]

open access: yesExploration of Cardiology
Exposure to ionizing radiation has recognized detrimental cancer and non-cancer health effects. These effects are now well-proven not only for high doses > 1,000 millisieverts (mSv) associated with head radiotherapy but also for moderate (100–1,000 mSv ...
Andrea Borghini
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

ESTIMATION OF THE MODERN DOSES OF AN ARTIFICIAL EXPOSURE FOR THE INHABITANTS OF THE SETTLEMENTS LOCATED ON THE COAST OF YENISEI IN A ZONE OF SUPERVISION OF FSUE «MINING AND CHEMICAL ESTABLISHMENT»

open access: yesРадиационная гигиена, 2015
The research objective consists in an estimation of modern exposure doses for the inhabitants of six settlements located on the coasts of the river Yenisei, including the doses caused by artificial radioactive contamination, connected with activity of ...
A. I. Grigorev   +3 more
doaj  

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