Results 91 to 100 of about 1,615,131 (338)
OBJECTIVES: This discussion paper aims to provide recommendations for the development of occupational exposure limits (OEL) for psychosocial hazards.
Roman Pauli +5 more
doaj +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Hubungan Paparan Debu Kayu dengan Kejadian Dermatitis Kontak Iritan pada Pekerja Mebel PT X Jepara [PDF]
Wood dust is an irritant substance and if it directly contact with the skin for a long time, it can cause workers exposed to the risk of irritant contact dermatitis.
Putri, F. Y. (Farah) +2 more
core
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Noise risk assessment and health surveillance in the Italian state police band musicians: A cross-sectional study [PDF]
Introduction: The State Police Band musicians are subjected to high levels of sound exposure during rehearsals and performances. This study assesses the noise risk among these musicians, employing various measurement and calculation methodologies to ...
Marco MICHELAZZI +7 more
doaj +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Every day occupational diseases incapacitate thousands of workers in a wide range of activities causing problems which vary from temporary retirements until death The diseases usually start when there is exposure to physical environmental agents above ...
Mayslane de Sousa Gomes +3 more
doaj +1 more source
Optimal Dynamic rading Strategies with Risk Limits [PDF]
Value at Risk (VaR) has emerged in recent years as a standard tool to measure and control the risk of trading portfolios.Yet,existing theoretical analyses of the optimal behavior of a trader subject to VaR limits have produced a negative view of VaR as a
Domenico Cuoco, Hua He, Sergei Issaenko
core

