Results 101 to 110 of about 2,670,025 (372)
We achieved cytoplasmic delivery of non‐cell‐penetrating IgGs by grafting a single functional complementarity‐determining region 1 (CDR1) from the light chain variable region (VL) of the cell‐internalizable 3D8 antibody. The engineered IgG acquired cell‐penetrating ability while maintaining antigen affinity, highlighting CDR1 grafting as a promising ...
Yerin Jeon+5 more
wiley +1 more source
Radon, thoron and their short lived progenies have a significant contribution to natural background radiation. Long term exposure of such radiation increases the probability of occurrence of cancer at low to moderate levels.
M. Ramsiya, Antony Joseph, P.J. Jojo
doaj +1 more source
Selection of appropriate multispectral camera exposure settings and radiometric calibration methods for applications in phenotyping and precision agriculture [PDF]
Radiometric accuracy of data is crucial in quantitative precision agriculture, to produce reliable and repeatable data for modeling and decision making. The effect of exposure time and gain settings on the radiometric accuracy of multispectral images was not explored enough.
arxiv +1 more source
Debiased inference for a covariate-adjusted regression function [PDF]
In this article, we study nonparametric inference for a covariate-adjusted regression function. This parameter captures the average association between a continuous exposure and an outcome after adjusting for other covariates. In particular, under certain causal conditions, this parameter corresponds to the average outcome had all units been assigned ...
arxiv
Occupational exposure to cobalt : a population toxicokinetic modeling approach validated by field results challenges the Biological Exposure Index for urinary cobalt [PDF]
International audienceThis study modeled the urinary toxicokinetics of cobalt exposure based on 507 urine samples from 16 workers, followed up for 1 week, and 108 related atmospheric cobalt measurements to determine an optimal urinary cobalt sampling ...
Bois, Frédéric Y.+3 more
core +3 more sources
Autophagy in cancer and protein conformational disorders
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source
The double exponential pulse waveform developed by the International Electrotechnical Commission is used to simulate the nuclear electromagnetic pulse, and the amplitude, spectrum, and phase of the main harmonic components of the waveform are analyzed. A
WANG Shixin, LU Mai
doaj +1 more source
Many studies into surface contamination of hospital environments have demonstrated that occupational exposure to cytotoxics through the dermal route remains a possible risk.
M. Crul+5 more
semanticscholar +1 more source
Effect of Concomitant 3-Hydroxy-3-Methyl-Glutaryl-CoA Reductase Inhibitor Therapy on Creatine Phosphokinase Levels and Mortality Among Patients Receiving Daptomycin: Retrospective Cohort Study. [PDF]
IntroductionThe prescribing information for daptomycin recommends discontinuing statin therapy during receipt of daptomycin. The literature supporting this recommendation is sparse.
Lodise, Thomas+4 more
core +1 more source
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang+2 more
wiley +1 more source