Results 101 to 110 of about 2,670,025 (372)

Cytoplasmic delivery of antibodies through grafting a functional single complementarity‐determining region loop

open access: yesFEBS Letters, EarlyView.
We achieved cytoplasmic delivery of non‐cell‐penetrating IgGs by grafting a single functional complementarity‐determining region 1 (CDR1) from the light chain variable region (VL) of the cell‐internalizable 3D8 antibody. The engineered IgG acquired cell‐penetrating ability while maintaining antigen affinity, highlighting CDR1 grafting as a promising ...
Yerin Jeon   +5 more
wiley   +1 more source

Estimation of indoor radon and thoron in dwellings of Palakkad, Kerala, India using solid state nuclear track detectors

open access: yesJournal of Radiation Research and Applied Sciences, 2017
Radon, thoron and their short lived progenies have a significant contribution to natural background radiation. Long term exposure of such radiation increases the probability of occurrence of cancer at low to moderate levels.
M. Ramsiya, Antony Joseph, P.J. Jojo
doaj   +1 more source

Selection of appropriate multispectral camera exposure settings and radiometric calibration methods for applications in phenotyping and precision agriculture [PDF]

open access: yes
Radiometric accuracy of data is crucial in quantitative precision agriculture, to produce reliable and repeatable data for modeling and decision making. The effect of exposure time and gain settings on the radiometric accuracy of multispectral images was not explored enough.
arxiv   +1 more source

Debiased inference for a covariate-adjusted regression function [PDF]

open access: yesarXiv, 2022
In this article, we study nonparametric inference for a covariate-adjusted regression function. This parameter captures the average association between a continuous exposure and an outcome after adjusting for other covariates. In particular, under certain causal conditions, this parameter corresponds to the average outcome had all units been assigned ...
arxiv  

Occupational exposure to cobalt : a population toxicokinetic modeling approach validated by field results challenges the Biological Exposure Index for urinary cobalt [PDF]

open access: yes, 2010
International audienceThis study modeled the urinary toxicokinetics of cobalt exposure based on 507 urine samples from 16 workers, followed up for 1 week, and 108 related atmospheric cobalt measurements to determine an optimal urinary cobalt sampling ...
Bois, Frédéric Y.   +3 more
core   +3 more sources

Autophagy in cancer and protein conformational disorders

open access: yesFEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Simulation research on electromagnetic field and temperature fields of nuclear electromagnetic pulse acting on human model

open access: yesFushe yanjiu yu fushe gongyi xuebao
The double exponential pulse waveform developed by the International Electrotechnical Commission is used to simulate the nuclear electromagnetic pulse, and the amplitude, spectrum, and phase of the main harmonic components of the waveform are analyzed. A
WANG Shixin, LU Mai
doaj   +1 more source

Occupational exposure of pharmacy technicians and cleaning staff to cytotoxic drugs in Dutch hospitals

open access: yesJournal of Occupational and Environmental Hygiene, 2020
Many studies into surface contamination of hospital environments have demonstrated that occupational exposure to cytotoxics through the dermal route remains a possible risk.
M. Crul   +5 more
semanticscholar   +1 more source

Effect of Concomitant 3-Hydroxy-3-Methyl-Glutaryl-CoA Reductase Inhibitor Therapy on Creatine Phosphokinase Levels and Mortality Among Patients Receiving Daptomycin: Retrospective Cohort Study. [PDF]

open access: yes, 2014
IntroductionThe prescribing information for daptomycin recommends discontinuing statin therapy during receipt of daptomycin. The literature supporting this recommendation is sparse.
Lodise, Thomas   +4 more
core   +1 more source

Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification

open access: yesFEBS Letters, EarlyView.
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang   +2 more
wiley   +1 more source

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