Results 191 to 200 of about 1,615,397 (338)

KCS1 and VIP1, the genes encoding yeast phosphoinositol pyrophosphate synthases, are required for Ca2+‐mediated response to dimethylsulfoxide (DMSO)

FEBS Open Bio, EarlyView.
Ca2+‐mediated response to DMSO was investigated in Saccharomyces cerevisiae cells expressing Ca2+‐dependent aequorin. Cell exposure to DMSO induced a cytosolic Ca2+ wave dependent on the integrity of the Cch1/Mid1 channel. Deletion of KCS1 or VIP1 genes encoding the phosphoinositol pyrophosphate (PP‐IP) synthases suppressed the DMSO‐induced Ca2 ...
Larisa Ioana Gogianu, Lavinia Liliana Ruta, Claudia Valentina Popa, Simona Ghenea, Ileana Cornelia Farcasanu   +4 more
wiley   +1 more source

Matrigel inhibits elongation and drives endoderm differentiation in aggregates of mouse embryonic stem cells

FEBS Open Bio, EarlyView.
Stem cell‐based embryo models (SCBEMs) are valuable to study early developmental milestones. Matrigel, a basement membrane matrix, is a critical substrate used in various SCBEM protocols, but its role in driving stem cell lineage commitment is not clearly defined.
Atoosa Amel, Rachel Brown, Alexa Rabeling, Mubeen Goolam   +3 more
wiley   +1 more source

Accurate low-dose exposure assessment of benzene and monoaromatic compounds by diffusive sampling: Sampling and analytical method validation according to ISO 23320 for radiello® samplers packed with graphitised charcoal and suitable for thermal desorption

Talanta Open
This research was aimed at providing an accurate low-dose benzene exposure assessment method, prospectively suitable to exposure limit values in the low ppb range, such as in the present-day chemical, petrochemical, foundry and pharmaceutical industry ...
Laura Zaratin, Caterina Boaretto, Riccardo Carnevale Schianca, George Hinkal, Elena Grignani, Danilo Cottica   +5 more
doaj  

Health and ecological risk assessment of metals in surface water from the Himalayan tributaries of the Ganga river, India. [PDF]

Geochem Trans
Azam MM, Tripathi JK.
europepmc   +1 more source

Threshold limit values and their applicability in the realms of chemical exposure control

, 2011
S. Soundararajan
openalex   +1 more source

Testing the coherence between occupational exposure limits for inhalation and their biological limit values with a generalized PBPK-model: The case of 2-propanol and acetone [PDF]

, 2014
Daan Huizer, Mark A. J. Huijbregts, Joost G.M. van Rooij, Ad M.J. Ragas   +3 more
openalex   +1 more source

Understanding and Overcoming Immunotherapy Resistance in Skin Cancer: Mechanisms and Strategies

Aging and Cancer, EarlyView.
This narrative review explores the mechanisms driving immunotherapy resistance in skin cancer, including tumor microenvironment factors, genetic mutations, and immune evasion strategies. It highlights potential strategies to overcome resistance, offering insights for improving therapeutic outcomes and guiding future research in personalized ...
Shreya Singh Beniwal, Abhimanyu Chiraparambil Radhakrishnan, Ayanchetty Haripraba, Saif Syed, Gajawada Pragna, Ayush Dwivedi, Akash Rawat, Daniela Castro Calderón, Martin Cevallos‐Cueva   +8 more
wiley   +1 more source

Spatial distribution and radiological hazards assessment of naturally occurring radionuclide materials in soil from quarry sites in Ogun State, Nigeria. [PDF]

Environ Monit Assess
Jegede DO, Afolabi TA, Agunbiade FO, Afolabi TA, Ogundiran OO, Gbadamosi MR, Sojinu SO, Ojekunle OZ, Varanusupakul P.   +8 more
europepmc   +1 more source

Aging‐Driven Blood–Brain Barrier Dysfunction and Its Impact on CNS Cancer Susceptibility: A Comprehensive Narrative Review

Aging and Cancer, EarlyView.
Aging weakens the blood–brain barrier (BBB), increasing susceptibility to CNS cancers and complicating treatment. This review examines BBB deterioration, its impact on drug delivery, and potential interventions like targeting neuroinflammation and advanced therapies.
Quang La, Aiman Baloch, David F. Lo
wiley   +1 more source

Heavy metals in spices from Lancaster, PA: arsenic, cadmium, and lead exposure risks and the need for regulation. [PDF]

Environ Monit Assess
Huff A, Lam H, Ghimirey A, Goldring J, Pimentel M, Okatch H.   +5 more
europepmc   +1 more source