Results 91 to 100 of about 528,613 (372)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Analysis and chromosomal mapping of Leishmania (Leishmania) amazonensis amastigote expressed sequence tags

open access: yesMemorias do Instituto Oswaldo Cruz, 2007
The characterization of expressed sequence tags (ESTs) generated from a cDNA library of Leishmania (Leishmania) amazonensis amastigotes is described. The sequencing of 93 clones generated new L. (L.) amazonensis ESTs from which 32% are not related to any
Luciana Girotto Gentil   +4 more
doaj   +1 more source

Gene discovery via expressed sequence tags from oil palm (Elaeis guineensis Jacq.) mesocarp. [PDF]

open access: yes, 2008
Expressed sequence tags (ESTs) have been used for many applications such as to reveal gene expression patterns, gene regulation and sequence diversity.
Abd. Wahab, Nurniwalis   +4 more
core  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Preliminary analysis of microsatellite markers derived from sugarcane expressed sequence tags (ESTs)

open access: yesGenetics and Molecular Biology, 2001
Expressed sequence tags (ESTs) in the sugarcane (Saccharum spp) database (SUCEST) were electronically searched and 402 microsatellites identified. Various dinucleotide and trinucleotide simple sequence repeat (SSR) motifs were found, with these being ...
Jorge A.G. da Silva
doaj   +1 more source

Rediscovery of Good-Turing estimators via Bayesian nonparametrics [PDF]

open access: yes, 2015
The problem of estimating discovery probabilities originated in the context of statistical ecology, and in recent years it has become popular due to its frequent appearance in challenging applications arising in genetics, bioinformatics, linguistics ...
Favaro, Stefano   +2 more
core   +4 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Expressed sequence tags in venomous tissue of Scorpaena plumieri (Scorpaeniformes: Scorpaenidae)

open access: yesNeotropical Ichthyology
Species of the family Scorpaenidae are responsible for accidents and sporadic casualties by the shore they inhabit. The species Scorpaena plumierifrom this family populate the Northeastern and Eastern coast of Brazil causing human envenomation ...
Fábio L. S. Costa   +5 more
doaj   +1 more source

Generation And Characterization Of Expressed Sequence Tags Of Oil Palm (Elaeis Guineensis) Root System [PDF]

open access: yes, 2005
Root system is an essential organ in plant for water and nutrient absorption, food storage and to support the plant within the soil. Construction of a cDNA library and analysis of the cDNA clones through ESTs approach have provided several advantages ...
Ng, Wai Har
core  

Gene trapping identifies transiently induced survival genes during programmed cell death [PDF]

open access: yes, 2001
Background: The existence of a constitutively expressed machinery for death in individual cells has led to the notion that survival factors repress this machinery and, if such factors are unavailable, cells die by default.
Wempe, Frank   +3 more
core   +1 more source

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