Analysis of expressed sequence tags of the cyclically parthenogenetic rotifer Brachionus plicatilis.
PLoS ONE, 2007 BackgroundRotifers are among the most common non-arthropod animals and are the most experimentally tractable members of the basal assemblage of metazoan phyla known as Gnathifera.
Koushirou Suga +4 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Development of type I genetic markers from expressed\ud sequence tags in highly polymorphic species
, 2011 Expressed sequence tag (EST) databases provide\ud a primary source of nuclear DNA sequences for genetic\ud marker development in non-model organisms. To date, the\ud process has been relatively inefficient for several reasons:\ud \ud - 1) priming site ...
Jung, Hyungtaek +2 more
core +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
The new conquistadors: Patent law and expressed sequence tags
, 2007 It's akin to the old Spanish, English and Portuguese explorers. They would take their boats until they found some edge of land, then they would go up and plant the flag of their king or queen. They didn't know what they'd discovered; how big it is, where
Rimmer, Matthew
core
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Retracted: Bioinformatic Deconstruction of Differentially Expressed Sequence Tags in Hepatocellular Carcinoma Based on Artificial Neural Network. [PDF]
Contrast Media Mol Imaging, 2023 Imaging CMM.
europepmc +1 more source
Rapid identification of new transcribed human sequences: a semi-ordered approach [PDF]
, 1995 Not ...
Dearlove, Andrew Martin
core
Distribution of the homology search of expressed sequence tags against the nr database.
, 2013 Distribution of the homology search of expressed sequence tags against the nr database.
Haiyang Xia (445568) +5 more
core +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source