Results 61 to 70 of about 12,358,530 (296)

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson   +3 more
wiley   +1 more source

Directional Statistics in Solar Potential of Rooftops at Three Different Neighborhoods of a Medium Size City

open access: yesProceedings, 2018
The utilization of solar energy is one of the best effective methods to combat the climate change. The estimation of solar potential in urban areas can vary depending on the urban morphology.
María-Eugenia Polo   +2 more
doaj   +1 more source

Modelling global solar radiation to optimise agricultural production

open access: yesSpanish Journal of Agricultural Research, 2021
Aim of study: To present a complete global radiation model that includes direct, diffuse sky and ground-reflected radiation, and compare the values with those obtained by the pyranometers.
Agustín Domínguez-Álvarez   +2 more
doaj   +1 more source

MicroRNAs regulate T-cell production of interleukin-9 and identify hypoxia-inducible factor-2a as an important regulator of T helper 9 and regularoty T-cell differentiation [PDF]

open access: yes, 2016
MicroRNAs (miRNAs) regulate many aspects of helper T cell (Th) development and function. Here we found that they are required for the suppression of interleukin‐9 (IL‐9) expression in Th9 cells and other Th subsets. Two highly related miRNAs (miR‐15b and
Baumjohann   +37 more
core   +2 more sources

EXPRESS: EXPressing REstful Semantic Services [PDF]

open access: yes2009 IEEE/WIC/ACM International Joint Conference on Web Intelligence and Intelligent Agent Technology, 2009
We introduce a new approach for RESTful Semantic Web Services called EXPRESS. It aims to exploit the similarities between REST and the Semantic Web, such as realization of resources, self describing representations, and uniform interfaces. EXPRESS is straightforward and systematic.
Alowisheq, Areeb, Millard, David
openaire   +1 more source

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski   +9 more
wiley   +1 more source

A minimal bile salt excretory pump promoter allows bile acid-driven physiological regulation of transgene expression from a gene therapy vector

open access: yesCell & Bioscience, 2022
Background Bile acid (BA) homeostasis is mainly regulated by bile salt excretory pump (BSEP), a hepatocyte transporter that transfers BAs to the bile.
Javier Martínez-García   +6 more
doaj   +1 more source

Ironing out the conflicts: iron supplementation reduces negatives bacterial interactions in the rhizosphere of an Atacama-endemic perennial grass

open access: yesEnvironmental Microbiome
Background In plants, root exudates selectively influence the growth of bacteria that colonize the rhizosphere. Bacterial communities associated with root systems are involved in macro and micronutrients cycling and organic matter transformation.
Constanza Aguado-Norese   +6 more
doaj   +1 more source

Estradiol regulates miR-135b and mismatch repair gene expressions via estrogen receptor-β in colorectal cells. [PDF]

open access: yes, 2012
Estrogen has anti-colorectal cancer effects which are thought to be mediated by mismatch repair gene (MMR) activity. Estrogen receptor (ER) expression is associated with microRNA (miRNA) expression in ER-positive tumors.
Fu, Lei   +6 more
core   +1 more source

MODALITY AND EXPRESSIBILITY [PDF]

open access: yesThe Review of Symbolic Logic, 2019
AbstractWhen embedding data are used to argue against semantic theoryAand in favor of semantic theoryB, it is important to ask whetherAcould make sense of those data. It is possible to ask that question on a case-by-case basis. But suppose we could show thatAcan make sense ofallthe embedding data whichBcan possibly make sense of. This would, on the one
openaire   +2 more sources

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