Results 121 to 130 of about 29,337,137 (262)

Pooling analysis on prognostic value of PHH3 expression in cancer patients

, 2018
Qian Hao,1,* Cong Dai,1,* Yujiao Deng,1,* Peng Xu,1 Tian Tian,1 Shuai Lin,1 Meng Wang,1 Kang Liu,1 Dingli Song,1 Ying Wu,1 Yan Guo,2 Zhijun Dai1 1Department of Oncology, Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an, People ...
Wang M, Hao Q, Liu K, Dai C, Xu P, Lin S, Guo Y, Song D, Tian T, Dai Z, Wu Y, Deng Y   +11 more
core  

Molecular cloning, characterization, and expression analysis of LeMYB1 from Lithospermum erythrorhizon

, 2014
MYB transcription factors (TFs) are known to have important functions in regulating the biosynthesis of secondary metabolites in plants. In this study, LeMYB1, a member of the MYB gene family of Lithospermum erythrorhizon, was cloned via the rapid ...
L. R. Kong, A. L. Zou, X. M. Wang, Y. H. Yang, W. J. Zhang, H. Zhao, S. K. Baloch, J. L. Qi   +7 more
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Beliefs about Emotional Expression [PDF]

, 2014
An essential aspect of effective counseling is the ability to understand clients’ emotions. There are times that clients may experience difficulty openly discussing their feelings during counseling sessions due to strong negative beliefs about emotional ...
Dooley, Leslie, Bishop, Lexia, Marino, Ali   +2 more
core  

Identification and expression analysis of the TST gene family in grapes

Xibei zhiwu xuebao
[Objective] Tonoplast sugar transporters (TSTs or TMTs) are crucial sugar transport proteins in plant development. The study aims to investigate the role of this gene family in grape growth and development, to provide a foundation for understanding the
YANG Jie, GONG Lili, XU Tao, ZHAO Shuangying, YANG Zhongyi, WU Yueyan   +5 more
doaj   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Semi Quantitative Expression Analysis of Potential Cancer Biomarkers [PDF]

, 2015
A cancer biomarker refers to a substance or process that is indicative of the presence of cancer it may be a molecule secreted by a tumor or a specific response of the body to the presence of cancer.
Tulsi Naik, K.S., Chandrashekaran, S., Manjunath, K., Anjana Raj, .   +3 more
core  

Genome-wide identification and expression analysis of the U-box E3 ubiquitin ligase gene family related to bacterial wilt resistance in tobacco (Nicotiana tabacum L.) and eggplant (Solanum melongena L.)

Frontiers in Plant Science
The E3 enzyme in the UPS pathway is a crucial factor for inhibiting substrate specificity. In Solanaceae, the U-box E3 ubiquitin ligase has a complex relationship with plant growth and development, and plays a pivotal role in responding to various biotic
Rui Chen, Gang Gu, Binghui Zhang, Chaofan Du, Xiaolu Lin, Weiwei Cai, Yan Zheng, Tong Li, Ruiqi Wang, Xiaofang Xie, Xiaofang Xie   +10 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source