Results 121 to 130 of about 4,331,351 (268)

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Identification and expression analysis of the TST gene family in grapes

open access: yesXibei zhiwu xuebao
[Objective] Tonoplast sugar transporters (TSTs or TMTs) are crucial sugar transport proteins in plant development. The study aims to investigate the role of this gene family in grape growth and development, to provide a foundation for understanding the
YANG Jie   +5 more
doaj   +1 more source

Gene Expression Analysis Methods on Microarray Data a A Review

open access: yes, 2014
In recent years a new type of experiments are changing the way that biologists and other specialists analyze many problems. These are called high throughput experiments and the main difference with those that were performed some years ago is mainly in ...
Prof G V Padma Raju
core  

Serial analysis of gene expression (SAGE)

open access: yes, 2007
In 1995, serial analysis of gene expression (SAGE) was developed as a versatile tool for gene expression studies. SAGE technology does not require pre-existing knowledge of the genome that is being examined and therefore SAGE can be applied to many ...
van Ruissen, Fred   +3 more
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Genome-wide identification and expression analysis of the U-box E3 ubiquitin ligase gene family related to bacterial wilt resistance in tobacco (Nicotiana tabacum L.) and eggplant (Solanum melongena L.)

open access: yesFrontiers in Plant Science
The E3 enzyme in the UPS pathway is a crucial factor for inhibiting substrate specificity. In Solanaceae, the U-box E3 ubiquitin ligase has a complex relationship with plant growth and development, and plays a pivotal role in responding to various biotic
Rui Chen   +10 more
doaj   +1 more source

Simcluster: clustering enumeration gene expression data on the simplex space

open access: yes, 2007
Transcript enumeration methods such as SAGE, MPSS, and sequencing-by-synthesis EST "digital northern", are important high-throughput techniques for digital gene expression measurement.
de B Pereira Carlos A   +19 more
core   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Role of Rubus chingii BBX gene family in anthocyanin accumulation during fruit ripening

open access: yesFrontiers in Plant Science
The B-box (BBX) family, which is a class of zinc finger transcription factors, exhibits special roles in plant growth and development as well as in plants’ ability to cope with various stresses.
Zhangting Xu   +8 more
doaj   +1 more source

A systems biology design and implementation of novel bioinformatics software tools for high throughput gene expression analysis

open access: yes, 2009
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Microarray technology has revolutionized the field of molecular biology by offering an efficient and cost effective platform for the simultaneous ...
Khan, Mohsin Amir Faiz
core  

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