Results 271 to 280 of about 8,188,103 (287)

Production of antibacterial compounds by a Steely hybrid polyketide synthase in Dictyostelium

FEBS Open Bio, EarlyView.
By selecting appropriate production species under optimised culture conditions, new chlorinated dibenzofuran compounds, which previously could not be analysed in sufficient quantities, were identified from cellular slime mould fruiting bodies. The strong antibacterial activity exhibited by these compounds suggests a link to the ecological function of ...
Tomoaki R. Yamashita, Toyonobu Usuki, Robert R. Kay, Tamao Saito   +3 more
wiley   +1 more source

De novo transcriptome assembly and gene expression analysis of Cnidium officinale under high-temperature conditions. [PDF]

BMC Genomics
Shin S, Han E, Seong H, Kim YI, Jung I, Jung W.   +5 more
europepmc   +1 more source

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

FEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel, Caroline Wozniak, Aya Sabri, Ben Haddad, Brooke Lopo, Alvaro Cobos, Sarah Sarofim, Jeffrey Guthrie, Deborah Heyl, Hedeel Guy Evans   +9 more
wiley   +1 more source

Comparative gene expression analysis in closely related dermatophytes reveals secondary metabolism as a candidate driver of virulence. [PDF]

Microbiol Spectr
Machová L, Kostovčík M, Švec K, Hubka V, Kolařík M, Wennrich A.   +5 more
europepmc   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

Expression analysis of the IL-23/Th17 pathway in children with rhinovirus infection. [PDF]

Ital J Pediatr
Teng S, Yu M, Qi Z, Zhao S, Wang H.
europepmc   +1 more source

Genome-wide characterization and expression analysis of the growth-regulating factor family in Mikania micrantha. [PDF]

BMC Plant Biol
Ma Y, Wang R, Sang Y, Wang T, Su Y.
europepmc   +1 more source

Comparing three algorithms of automated facial expression analysis in autistic children: different sensitivities but consistent proportions. [PDF]

Mol Autism
Manelis-Baram L, Barami T, Ilan M, Meiri G, Menashe I, Soskin E, Sofer C, Dinstein I.   +7 more
europepmc   +1 more source