Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Molecular characterization and expression analysis of GATA1 in the blood clam Anadara granosa reveals its role in gonadal development. [PDF]
Xu Y +5 more
europepmc +1 more source
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
Allele-specific immune gene quantification and expression analysis in single-cell RNA-seq data. [PDF]
Al Ajami A +3 more
europepmc +1 more source
Differential gene expression analysis of Dohne Merino sheep naturally infected with Haemonchus contortus. [PDF]
Ramantswana TM +5 more
europepmc +1 more source
Integration of exosome-related genes and differential expression analysis reveals potential biomarkers for prostate cancer. [PDF]
Huang S +7 more
europepmc +1 more source
Genome-wide identification of AAAP gene family and expression analysis under abiotic stresses in Avena sativa. [PDF]
Ling L, Wang S, Zhang H, Yang F, Qu L.
europepmc +1 more source
MicroRNA identification and expression analysis of wheat thermo-sensitive male sterile line BNS366 for fertility transformation. [PDF]
Chen J +8 more
europepmc +1 more source
Genome-Wide Identification and Expression Analysis of the AS2/LOB Transcription Factor Family in <i>Asparagus officinalis</i>. [PDF]
Ye X +14 more
europepmc +1 more source
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Comparative gene-expression analysis
Trends in Biotechnology, 1999The study of differences in gene-expression patterns is one of the most promising approaches for understanding mechanisms of differentiation and development. In addition, the identification of disease-related target molecules opens new avenues for rational pharmaceutical intervention.
D H, Kozian, B J, Kirschbaum
openaire +2 more sources

