Results 291 to 300 of about 8,341,413 (332)

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Molecular characterization and expression analysis of GATA1 in the blood clam Anadara granosa reveals its role in gonadal development. [PDF]

BMC Genomics
Xu Y, Zhang C, Zhang L, Wang J, Liu H, Bao Y.   +5 more
europepmc   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

Allele-specific immune gene quantification and expression analysis in single-cell RNA-seq data. [PDF]

NAR Genom Bioinform
Al Ajami A, Schuck J, Marini F, Imkeller K.   +3 more
europepmc   +1 more source

Differential gene expression analysis of Dohne Merino sheep naturally infected with Haemonchus contortus. [PDF]

Sci Rep
Ramantswana TM, Malatji DP, Pierneef RE, Soma P, Van Der Nest MA, Muchadeyi FC.   +5 more
europepmc   +1 more source

Integration of exosome-related genes and differential expression analysis reveals potential biomarkers for prostate cancer. [PDF]

Discov Oncol
Huang S, Hu C, Guo Z, Zhang X, Wu T, Zeng Y, Qing C, Cheng S.   +7 more
europepmc   +1 more source

Genome-wide identification of AAAP gene family and expression analysis under abiotic stresses in Avena sativa. [PDF]

BMC Genomics
Ling L, Wang S, Zhang H, Yang F, Qu L.
europepmc   +1 more source

MicroRNA identification and expression analysis of wheat thermo-sensitive male sterile line BNS366 for fertility transformation. [PDF]

Front Plant Sci
Chen J, Hu X, Song R, Sun G, Huang S, Hua W, Zhu J, Zhang D, Ren X.   +8 more
europepmc   +1 more source

Genome-Wide Identification and Expression Analysis of the AS2/LOB Transcription Factor Family in <i>Asparagus officinalis</i>. [PDF]

Genes (Basel)
Ye X, Li Y, Zhong SF, Huang WN, Zeng J, Zuo Q, Li S, Sun P, Tao S, Huang L, Zhong MZ, Zhao WJ, Shen YX, Tao Y, Deng JQ.   +14 more
europepmc   +1 more source

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Comparative gene-expression analysis

Trends in Biotechnology, 1999
The study of differences in gene-expression patterns is one of the most promising approaches for understanding mechanisms of differentiation and development. In addition, the identification of disease-related target molecules opens new avenues for rational pharmaceutical intervention.
D H, Kozian, B J, Kirschbaum
openaire   +2 more sources