Results 311 to 320 of about 33,209,906 (421)
The roles and applications of extracellular vesicles in cancer
Extracellular vesicles (EVs) are minute versions of cells limited by a lipid bilayer containing cytoplasm from the cell that releases them, but without a nucleus and thus unable to self‐reproduce. EVs contain multiple molecules (proteins, lipids, glycans, and nucleic acids) they can induce complex responses in cells.
Clotilde Théry, Daniel Louvard
wiley +1 more source
Co-Expression Analysis of the ZDHHC19 Palmitoyltransferase-miR-4733-miR-596 Putative Regulatory Axis in Sepsis. [PDF]
Maricza K+8 more
europepmc +1 more source
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan+10 more
wiley +1 more source
Exploring and mitigating shortcomings in single-cell differential expression analysis with a new statistical paradigm. [PDF]
Wu CH, Zhou X, Chen M.
europepmc +1 more source
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim+8 more
wiley +1 more source
Gene Co-Expression Analysis Reveals Functional Differences Between Early- and Late-Onset Alzheimer's Disease. [PDF]
Gutiérrez Cruz AI+2 more
europepmc +1 more source
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka+10 more
wiley +1 more source
Immuno- and expression analysis of Ehrlichia canis immunoreactive proteins. [PDF]
Patel JG, Luo T, Zhang X, McBride JW.
europepmc +1 more source