Results 91 to 100 of about 1,642,960 (338)

Expressing aspectual interactions in requirements engineering: Experiences, problems and solutions

open access: yesScience of Computer Programming, 2012
AbstractAspect Oriented Requirements Engineering (AORE) provides support for modularizing crosscutting requirements. In the context of an industrial project in the domain of Slot Machines we needed to perform AORE, with a special emphasis on dependencies and interactions among concerns.
Zambrano Polo y La Borda, Arturo Federico   +2 more
openaire   +5 more sources

Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation

open access: yesFEBS Letters, EarlyView.
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley   +1 more source

Codes et intelligences : externalisation, retour sur soi et brouillage des frontières entre nature et culture

open access: yesSociologies, 2019
The article retains four types of codes and intelligences, according to their historical order of appearance: 1) DNA codes, associated with genomic intelligence, 2) neural codes, associated with sensory-motor intelligence, 3) linguistic codes, associated
André Petitat
doaj  

A Novice-Friendly and Accessible Networked Educational Robotics Simulation Platform

open access: yesEducation Sciences
Despite its potential for STEM education, educational robotics remains out of reach for many classrooms due to upfront purchase costs, maintenance requirements, storage space, and numerous other barriers to entry.
Gordon Stein   +4 more
doaj   +1 more source

Autophagy in cancer and protein conformational disorders

open access: yesFEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Paired microbiome and metabolome analyses associate bile acid changes with colorectal cancer progression

open access: yesCell Reports, 2023
Summary: Colorectal cancer (CRC) is driven by genomic alterations in concert with dietary influences, with the gut microbiome implicated as an effector in disease development and progression.
Ting Fu   +25 more
doaj  

Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification

open access: yesFEBS Letters, EarlyView.
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang   +2 more
wiley   +1 more source

An integrated system for weblog study [PDF]

open access: yes, 2004
Thesis (M. Eng.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2004.Includes bibliographical references (p. 17).Weblogs, personal online journals, are a new medium for expression and communication.
Oshiro, Makanaokalani, 1981-
core  

Accurate and Efficient Mapping of the Cross-Linked microRNA-mRNA Duplex Reads

open access: yesiScience, 2019
Summary: MicroRNA (miRNA) trans-regulates the stability of many mRNAs and controls their expression levels. Reconstruction of the miRNA-mRNA interactome is key to the understanding of the miRNA regulatory network and related biological processes. However,
Cuncong Zhong, Shaojie Zhang
doaj  

On binary decision hypertree (hyperdiagram) [PDF]

open access: yesAUT Journal of Mathematics and Computing
In computer science, a binary decision diagram is a data structure that is used to represent a Boolean function and to consider a compressed representation of relations.
Mohammad Hamidi, Marzieh Rahmati
doaj   +1 more source

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