Results 181 to 190 of about 1,656,664 (330)

A novel facial expression recognition framework using deep learning based dynamic cross-domain dual attention network. [PDF]

PeerJ Comput Sci
Alzahrani AO, Alghamdi AM, Ashraf MU, Ilyas I, Sarwar N, Alzahrani A, Alarood AAS.   +6 more
europepmc   +1 more source

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias, Ana Oitabén, Sonia Zumalave, Bernardo Rodriguez‐Martin, María Gallardo‐Gómez, Martín Santamarina, Ana Pequeño‐Valtierra, Laura Juaneda‐Magdalena, Ramón García‐Escudero, José Luis López‐Cedrún, Máximo Fraga, José M. C. Tubio, Mónica Martínez‐Fernández   +12 more
wiley   +1 more source

Differentiable graph clustering with structural grouping for single-cell RNA-seq data. [PDF]

Bioinformatics
Yan X, Du S, Zou Q, Tian Z.
europepmc   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Foundation Model: A New Era for Plant Single-cell Genomics. [PDF]

Genomics Proteomics Bioinformatics
Zeng 曾远松 Y, Yang 杨跃东 Y.
europepmc   +1 more source

Process Behaviour: Formulae vs. Tests

PUBLISHED Paris, France Process behaviour is often defined either in terms of the tests they satisfy, or in terms of the logical properties they enjoy. Here we compare these two approaches, using extensional testing in the style of DeNicola, Hennessy, and a recursive version of the property logic HML.
openaire   +1 more source

Une approche pour la représentation et la simplification des expressions booléennes

, 1996
Dans ce papier, nous nous intéressons au problème de réduction (ou simplification) des expressions booléennes. Nous présentons une approche différente des approches connues, telles que celles de Karnaugh et Quine-Mc Clusky. L'expression est modélisée sous la forme de chemins d'expression comprenant des termes ascendants et descendants.
openaire   +1 more source

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

Molecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach, Nilesh Chatterjee, Kellie Spahr, Gilberto Serrano de Almeida, Anabel Varela‐Carver, Taimur T. Shah, Mathias Winkler, Hashim U. Ahmed, Charlotte L. Bevan   +8 more
wiley   +1 more source

Leveraging transcription factor physical proximity for enhancing gene regulation inference. [PDF]

Bioinformatics
Huang X, Hullur AR, Jafari E, Shridhar K, Zhou M, Mackie K, Huang K, Wang Y.   +7 more
europepmc   +1 more source

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

Molecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche, Renske Imschoot, Béatrice Lintermans, Lode Denolf, Joachim Taminau, Charlotte Fieuws, Geert Berx, Kris Gevaert, Kathleen B. M. Claes   +8 more
wiley   +1 more source