Results 221 to 230 of about 1,344,767 (284)

Regulatory role of LncRNA FMR1-AS1 in the pathogenesis of alzheimer's disease based on bioinformatics and in vitro experimental validation. [PDF]

Sci Rep
Yu X, Cai H, He C, Ouyang Z, Li Y, Chen L.   +5 more
europepmc   +1 more source

TREX1, a predator for treating MSI‐H tumors?

Molecular Oncology, EarlyView.
Immunotherapy benefits many patients; yet, some with MSI‐H tumors remain unresponsive despite their high immunogenicity. Xu et al. reveal that TREX1 enables immune evasion by degrading cytosolic DNA and suppressing cGAS–STING–IFN‐I signaling. TREX1 loss restores DNA sensing, increases CD8+ T and NK cell infiltration, and boosts antitumor immunity ...
Elena Benidovskaya, Joséphine Deneft, Marc Van den Eynde   +2 more
wiley   +1 more source

GAN-AVI: facial expression translator in Twitter avatar analogous to tweet sentiments. [PDF]

Sci Rep
Devi KDS, Muppavaram K, Atheeq C, Shaikh A, Alqazzaz A, Al Reshan MS, Alqhtani SM, Alalhareth M.   +7 more
europepmc   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

MUSE: A Multi-slice Joint Analysis Method for Spatial Transcriptomics Experiments. [PDF]

Proc ACM Int Conf Inf Knowl Manag
Duan Z, Li X, Xiao Z, Ying R, Zhang J.
europepmc   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

The consolidation of open-source computer-assisted chemical synthesis data into a comprehensive database. [PDF]

J Cheminform
Hasic H, Ishida T.
europepmc   +1 more source

YOLO11m-cls applied to sex and age classification based on the radiographic analysis of the nasal aperture. [PDF]

Sci Rep
Scavassini L, Silva R, Khan A, Anees W, Murray J, Angelakopoulos N, Arakelyan M, Porto L, Abade A, Franco A.   +9 more
europepmc   +1 more source

Image Captioning with Object Detection and Facial Expression Recognition for Smart Industry. [PDF]

Bioengineering (Basel)
Khan AS, Khan AH, Abbass MJ, Shafi I.
europepmc   +1 more source

Dynamic versus static facial color changes: Evidence for terminal color dominance in expression recognition. [PDF]

J Vis
Shibusawa M, Hasegawa Y, Tamura H, Nakauchi S, Minami T.   +4 more
europepmc   +1 more source