Results 241 to 250 of about 234,285 (301)

From Cell-Free Transcriptomes to Single-Cell Landscapes: Biomarker Discovery and Originating Cell Alteration Analysis via Graph Matrix Factorization. [PDF]

Adv Sci (Weinh)
Zhang W, Zhang W, Wei H, Liu S, Shang J, Gong W, Cheng H, Lei X, Kou Y, Jiang B.   +9 more
europepmc   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Uncovering Prognostic Biomarkers Underlying Hepatocellular Carcinoma Through Integrative Multi-Omics and a Network-Based Approach. [PDF]

Int J Mol Sci
Rahmani AH, Beg A, Sarwar T, Khan AA.
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

DeepDRP: Dose-response predictions of drug pairs using deep learning based on data-driven feature representation and dose-response curve characteristics. [PDF]

PLoS One
Moragheb M, Dehghan A, Razzaghi P, Gharaghani S.   +3 more
europepmc   +1 more source

Signal-based spatial domain identification of spatially resolved transcriptomics with multigraph fusion. [PDF]

Brief Bioinform
Ma Y, Wang Y, Ma X.
europepmc   +1 more source

Innovations in Deaf Health Care Communication: Systematic Review of Sign Language Recognition Systems. [PDF]

J Med Internet Res
Marcolino MS, Oliveira LFR, Valle LR, Rosa LMMS, Sanches GTS, Santos NS, Costa MRD, Bernardino ELA, Cordeiro RAA, Prates RO, Reis ZSN, Campos MFM.   +11 more
europepmc   +1 more source

DeepSGE: predicting spatial gene expression using residual network with efficient channel attention and dynamic graph attention network. [PDF]

BMC Genomics
Yuan L, Jiang Y, Wang Q, Hu C, Li G, Zheng CH.   +5 more
europepmc   +1 more source

Trends and Prospects of Biometrics: From Sensing to Perception and Cognition. [PDF]

Sensors (Basel)
Cao Z, Schmid N, Pang L.
europepmc   +1 more source

DeepLMI: deep feature mining with a globally enhanced graph convolutional network for robust lncRNA-miRNA interaction prediction. [PDF]

Bioinformatics
Huang Z, Chen K, Wang X, Wang J, Shen S, Zhang Y, Wu M, Deng L.   +7 more
europepmc   +1 more source