Results 1 to 10 of about 127,404 (120)
Left-right asymmetry in oxidative stress sensing neurons in C. elegans
microPublication Biology, 2022 Perception of oxidative stress in nematodes involves specific neurons expressing antioxidant enzymes. Here, we carefully characterized GFP knock-in lines for C. elegans peroxiredoxin PRDX-2 and thioredoxin TRX-1, and uncovered that left and right I2, PHA
Sophie Quintin, Gilles Charvin
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Post-embryonic endogenous expression and localization of LET-60/Ras in C. elegans
microPublication Biology, 2023 Ras GTPases regulate many developmental and physiological processes and mutations in Ras are associated with numerous human cancers. Here, we report the function, levels, and localization of an N-terminal knock-in of mNeonGreen (mNG) into C.
Ranjay Jayadev +2 more
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Characterization of RNA in exosomes secreted by human breast cancer cell lines using next-generation sequencing [PDF]
PeerJ, 2013 Exosomes are nanosized (30–100 nm) membrane vesicles secreted by most cell types. Exosomes have been found to contain various RNA species including miRNA, mRNA and long non-protein coding RNAs. A number of cancer cells produce elevated levels of exosomes.
Piroon Jenjaroenpun +5 more
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A browser for expression data [PDF]
Bioinformatics, 2000 Abstract Summary: We have written a fully extensible Java application for visually browsing expression data, and clusters of genes or experimental conditions calculated from that data. The application requires a runtime environment for Java2. Availability: http://www.sanger.ac.uk/Users/mrp/java/ExpressionBrowser
Pocock, M R, Hubbard, T J
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microPublication Biology, 2023 SnoRNAs are frequently processed into snoRNA-derived RNAs (sdRNAs) that function much like traditional microRNAs (miRNAs). That said, our analyses suggest a global switch from DICER-dependent (predominately miRNA) to DICER-independent (predominately ...
Noel L Godang +7 more
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Expression Data Analysis with Reactome [PDF]
Current Protocols in Bioinformatics, 2015 AbstractThe Reactome database of curated biological pathways provides a tool for visualizing user‐supplied expression data as an overlay on pathway diagrams, thereby affording an effective means to examine expression of the constituents of the pathway and determine whether all that are necessary are present.
Steve, Jupe +2 more
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microPublication Biology, 2023 Mutations in TDP-43 are known to cause Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD). TDP-43 binds to and regulates splicing of several RNA including Zmynd11.
Ramesh K. Narayanan +8 more
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An atonal homolog, lin-32, regulates hypodermal morphogenesis in Caenorhabditis elegans
microPublication Biology, 2023 The transcription factor atonal contributes to patterning and cell fate determination in specialized epithelial cells in various animals, but its function in hypodermis is unknown. Here, we analyzed the atonal homolog lin-32 in C.
Sayaka Hori, Shohei Mitani
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Matching Regular Expressions on uncertain data [PDF]
Algorithmica, 2022 AbstractIn this paper we study regular expression matching in cases in which the identity of the symbols received is subject to uncertainty. We develop a model of symbol emission and uses a modification of the shortest path algorithm to find optimal matches on the Cartesian Graph of an expression provided that the input is a finite list. In the case of
José Arturo Gil, Simone Santini
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Developmental origin of the Pair1 descending interneuron
microPublication Biology, 2022 Pair1 is part of a Drosophila larval locomotor circuit that promotes backward locomotion by inhibiting forward locomotion. We hypothesize that lineage related neurons may function in neuronal circuits together.
Amanda Linskens, Chris Doe, Kristen Lee
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