Results 121 to 130 of about 12,776,966 (376)

Correlation Patterns Between DNA Methylation and Gene Expression in The Cancer Genome Atlas

Cancer Informatics, 2019
Background: DNA methylation is a form of epigenetic modification that has been shown to play a significant role in gene regulation. In cancer, DNA methylation plays an important role by regulating the expression of oncogenes.
John Cg Spainhour, H. S. Lim, S. Yi, P. Qiu   +3 more
semanticscholar   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Temporal candidate gene expression patterns in the sow placenta during early gestation and the effect of maternal L-arginine supplementation [PDF]

, 2020
Sanja Novak, Harry S. Moore, France-Hélène Paradis, Gordon K. Murdoch, Michael K. Dyck, W. T. Dixon, G. R. Foxcroft   +6 more
openalex   +1 more source

Distinct Expression Patterns of Genes Coding for Biological Response Modifiers Involved in Inflammatory Responses and Development of Fibrosis in Chronic Hepatitis C: Upregulation of SMAD-6 and MMP-8 and Downregulation of CAV-1, CTGF, CEBPB, PLG, TIMP-3, MMP-1, ITGA-1, ITGA-2 and LOX [PDF]

, 2022
Leona Radmanić, Petra Korać, Lana Gorenec, Petra Šimičić, Kristian Bodulić, Adriana Vince, Snježana Židovec Lepej   +6 more
openalex   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Genome-wide characterization and expression analysis of LBD transcription factors in Ziziphus jujuba var. spinosa: putative roles in tissue development and abiotic stress adaptation

Frontiers in Plant Science
The plant-specific Lateral Organ Boundaries Domain (LBD) transcription factors (TFs) are critical regulators of the expression of genes related to tissue development and stress responses. Sour jujube (Ziziphus jujuba var.
Meng Li, Qiaoyun Zhang, Shuhui Zhou, Ruixue Wang, Yao Zhao, Jibiao Geng   +5 more
doaj   +1 more source

DNA methylation patterns and epigenetic memory.

Genes & Development, 2002
The character of a cell is defined by its constituent proteins, which are the result of specific patterns of gene expression. Crucial determinants of gene expression patterns are DNA-binding transcription factors that choose genes for transcriptional ...
A. Bird
semanticscholar   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Characterization and expression analysis of transcription factors in Spartina alterniflora unveil their critical roles in salt stress resistance

Frontiers in Plant Science
IntroductionTranscription factors (TFs) are essential regulators of gene expression, orchestrating plant growth, development, and responses to environmental stress. Spartina alterniflora, a halophytic species renowned for its exceptional salt resistance,
Yuanyuan Jiang, Yuanyuan Jiang, Yuanyuan Jiang, Shoukun Chen, Shoukun Chen, Shoukun Chen, Shuqiang Gao, Shuqiang Gao, Shuqiang Gao, Jiahui Geng, Jiahui Geng, Qin Shu, Qin Shu, Shang Gao, Shang Gao, Huihui Li, Huihui Li   +16 more
doaj   +1 more source

A Leveraged Signal-to-Noise Ratio (LSTNR) Method to Extract Differentially Expressed Genes and Multivariate Patterns of Expression From Noisy and Low-Replication RNAseq Data

Frontiers in Genetics, 2018
To life scientists, one important feature offered by RNAseq, a next-generation sequencing tool used to estimate changes in gene expression levels, lies in its unprecedented resolution.
Oswaldo A. Lozoya, Janine H. Santos, Richard P. Woychik   +2 more
doaj   +1 more source