Results 231 to 240 of about 12,776,966 (376)

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Genome-Wide Characterization of the <i>HOX</i> Gene Family: Evolution and Expression Patterns in Donkey. [PDF]

Int J Mol Sci
Liu X, Liu A, Khan MZ, Zhu Q, Zheng Y, Chen W, Cai B, Yan Z, Peng Y, Wang C.   +9 more
europepmc   +1 more source

Placental PAGs: gene origins, expression patterns, and use as markers of pregnancy.

Reproduction, 2015
R. Wallace, K. Pohler, M. Smith, Jonathan A Green   +3 more
semanticscholar   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

RECQL4 alterations in gliomas and nerve sheath tumors: Expression patterns and therapeutic implications. [PDF]

J Neuropathol Exp Neurol
Belakhoua S, Lopez G, Dubey S, Rai S, Chen L, Chen S, Pallavajjala A, Yuan M, Pekmezci M, Stojanova M, Heaphy CM, Eberhart CG, Rodriguez FJ.   +12 more
europepmc   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Conservation of gene expression patterns between the amniotic and nasal epithelium at birth. [PDF]

ERJ Open Res
Hancock DG, Agudelo-Romero SP, Kicic-Starcevich E, Lim J, Karpievitch YV, Zhang G, Martino DJ, Kicic A, Iosifidis T, Stick SM.   +9 more
europepmc   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Gene Expression Patterns in Lung Adenocarcinoma Cells in Response to Changes in Deuterium Concentration. [PDF]

Int J Mol Sci
Csonka GI, Papp A, Somlyai I, Somlyai G.
europepmc   +1 more source

Gene expression patterns in relation to the clinical phenotype in Klinefelter syndrome.

Journal of Clinical Endocrinology and Metabolism, 2015
M. Zitzmann, R. Bongers, S. Werler, N. Bogdanova, J. Wistuba, S. Kliesch, J. Gromoll, F. Tüttelmann   +7 more
semanticscholar   +1 more source