Results 241 to 250 of about 12,776,966 (376)

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Peripheral MicroRNA Expression Patterns as Biomarkers for Adolescent Depression. [PDF]

Biol Psychiatry Glob Open Sci
Levone BR, Schratt G.
europepmc   +1 more source

A Prospective Multi-Institutional Observational Study on ER, PR, HER2/NEU, and Ki-67 Expression and Discordance Pattern in Primary and Metastatic and Recurrent Carcinoma Breast and Its Therapeutic Implications and Prognostic Outcome

, 2022
M Satishkumar, Muthuvel Ramesh, Jeevan G. Sanjive   +2 more
openalex   +2 more sources

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

MRI-derived atrophy in multiple system atrophy aligns with mitochondrial and glial gene expression patterns. [PDF]

NPJ Parkinsons Dis
Chougar L, Tremblay C, Delva A, Filiatrault M, Vo A, Hansen JY, Farahani A, Misic B, Khalafi P, Castonguay CE, Rouleau G, Corvol JC, Vidailhet M, Degos B, Pyatigorskaya N, Payan C, Grabli D, Lehéricy S, Dagher A, Rahayel S.   +19 more
europepmc   +1 more source

Epigenomic analysis of the HOX gene loci reveals mechanisms that may control canonical expression patterns in AML and normal hematopoietic cells

Leukemia, 2015
D. Spencer, Margaret A. Young, T. Lamprecht, Nichole M. Helton, Robert S. Fulton, M. O'Laughlin, C. Fronick, V. Magrini, Ryan T. Demeter, C. A. Miller, J. Klco, R. Wilson, T. Ley   +12 more
semanticscholar   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

ANXA13 expression patterns in hepatocellular carcinoma and impact on tumor behavior. [PDF]

World J Gastrointest Surg
Yang SK, Zhao XK, Cui YY, Liu DZ, Zhao ZJ, Zhou L, Wang L, Zhang F.   +7 more
europepmc   +1 more source

Additional file 4 of RNAseq expression patterns of canine invasive urothelial carcinoma reveal two distinct tumor clusters and shared regions of dysregulation with human bladder tumors

, 2020
Heidi G. Parker, Deepika Dhawan, Alex C. Harris, José A. Ramos‐Vara, Brian W. Davis, Deborah W. Knapp, Elaine A. Ostrander   +6 more
openalex   +1 more source

Author response: Exploring the expression patterns of palmitoylating and de-palmitoylating enzymes in the mouse brain using the curated RNA-seq database BrainPalmSeq

, 2022
Angela R. Wild, Peter William Hogg, Stéphane Flibotte, Glory G Nasseri, Rocio Hollman, Danya Abazari, Kurt Haas, Shernaz X. Bamji   +7 more
openalex   +1 more source