Results 51 to 60 of about 12,776,966 (376)

Analysis of allelic expression patterns in clonal somatic cells by single-cell RNA-seq

Nature Genetics, 2016
Cellular heterogeneity can emerge from the expression of only one parental allele. However, it has remained controversial whether, or to what degree, random monoallelic expression of autosomal genes (aRME) is mitotically inherited (clonal) or stochastic (
B. Reinius, Jeff E. Mold, D. Ramsköld, Q. Deng, P. Johnsson, J. Michaëlsson, J. Frisén, R. Sandberg   +7 more
semanticscholar   +1 more source

Personalizing the Pediatric Hematology/Oncology Fellowship: Adapting Training for the Next Generation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT The pediatric hematology‐oncology fellowship training curriculum has not substantially changed since its inception. The first year of training is clinically focused, and the second and third years are devoted to scholarship. However, this current structure leaves many fellows less competitive in the current job market, resulting in ...
Scott C. Borinstein, Melissa J. Rose, Scott Moerdler, Richard Ho   +3 more
wiley   +1 more source

Identification and expression pattern analysis of the OsCBL gene family in rice

Frontiers in Plant Science
Calcium (Ca2+) signaling, which is mediated by calcineurin B-like proteins (CBLs), plays a pivotal role in the way that plants respond to abiotic stresses.
Zhao Hu, Fengpu Xie, Lu Cai, Run Qian
doaj   +1 more source

Genome-Wide Identification and Expression of the GRAS Gene Family in Oat (Avena sativa L.)

Agronomy, 2023
The GRAS protein family is involved in plant growth and development, plant disease resistance, and abiotic stress response. Although the GRAS protein family has been systematically studied and reported in many plants, it has not been reported in oat, an ...
Rui Wu, Wenhui Liu, Kaiqiang Liu, Guoling Liang, Yue Wang   +4 more
doaj   +1 more source

Positional information, positional error, and read-out precision in morphogenesis: a mathematical framework

, 2014
The concept of positional information is central to our understanding of how cells in a multicellular structure determine their developmental fates.
Dubuis, Julien O, Gregor, Thomas, Petkova, Mariela D, Tkačik, Gašper   +3 more
core   +1 more source

Psychosocial Outcomes in Patients With Endocrine Tumor Syndromes: A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction The combination of disease manifestations, the familial burden, and varying penetrance of endocrine tumor syndromes (ETSs) is unique. This review aimed to portray and summarize available data on psychosocial outcomes in patients with ETSs and explore gaps and opportunities for future research and care.
Daniël Zwerus, Floortje Strobbe, Annemarie A. Verrijn Stuart, Hanneke M. van Santen, Gerlof D. Valk, Sasja A. Schepers, Rachel S. van Leeuwaarde   +6 more
wiley   +1 more source

In planta localisation patterns of MADS domain proteins during floral development in Arabidopsis thaliana [PDF]

, 2009
Background: MADS domain transcription factors play important roles in various developmental processes in flowering plants. Members of this family play a prominent role in the transition to flowering and the specification of floral organ identity. Several
Angenent, G.C., Folter, S., de, Immink, G.H., Kaufmann, K., Shchennikova, A., Urbanus, S.L.   +5 more
core   +3 more sources

Gene Expression Patterns in Ovarian Carcinomas [PDF]

Molecular Biology of the Cell, 2003
We used DNA microarrays to characterize the global gene expression patterns in surface epithelial cancers of the ovary. We identified groups of genes that distinguished the clear cell subtype from other ovarian carcinomas, grade I and II from grade III serous papillary carcinomas, and ovarian from breast carcinomas.
Marci E, Schaner, Douglas T, Ross, Giuseppe, Ciaravino, Therese, Sorlie, Olga, Troyanskaya, Maximilian, Diehn, Yan C, Wang, George E, Duran, Thomas L, Sikic, Sandra, Caldeira, Hanne, Skomedal, I-Ping, Tu, Tina, Hernandez-Boussard, Steven W, Johnson, Peter J, O'Dwyer, Michael J, Fero, Gunnar B, Kristensen, Anne-Lise, Borresen-Dale, Trevor, Hastie, Robert, Tibshirani, Matt, van de Rijn, Nelson N, Teng, Teri A, Longacre, David, Botstein, Patrick O, Brown, Branimir I, Sikic   +25 more
openaire   +2 more sources

Nutritional and Behavioral Intervention for Long‐Term Childhood Acute Leukemia Survivors With Metabolic Syndrome

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Metabolic syndrome (MetS) is a common complication in survivors of childhood acute lymphoblastic and myeloid leukemia (AL), and a major risk factor for premature cardiovascular disease, type‐2‐diabetes, and metabolic dysfunction‐associated steatotic liver disease (MASLD).
Visentin Sandrine, Béliard Sophie, Renard Cécile, Caussy Cyrielle, Hamidou Zeinab, Romano David, Gacem Mélanie, Petit Arnaud, Saultier Paul, Borentain Patrick, Michel Gérard   +10 more
wiley   +1 more source

Genome-Wide Identification, Classification, Expression Analysis, and Screening of Drought and Heat Resistance-Related Candidates of the Rboh Gene Family in Wheat

Plants
Plant respiratory burst oxidase homologs (Rbohs) are key enzymes that produce reactive oxygen species (ROS), which serve as signaling molecules regulating plant growth and stress responses.
Miyuan Cao, Yue Zhang, Xiaoxiao Zou, Huangping Yin, Yan Yin, Zeqi Li, Wenjun Xiao, Shucan Liu, Yongliang Li, Xinhong Guo   +9 more
doaj   +1 more source