Results 41 to 50 of about 1,048,335 (246)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Protein expression profile and microRNA expression signature in estrogen receptor-positive and -negative breast cancers: report of two cases

Breast Cancer: Targets and Therapy, 2018
Yuko Tsunoda,1 Akiko Sasaki,2 Naomi Sakamoto,1 Kou Teraoka,1 Rie Nakagawa,1 Yoshitomo Koshida,1 Eisuke Fukuma1 1Department of Breast Surgery, Breast Center, Kameda Medical Center, Chiba, Japan; 2Department of Pharmacology, Showa University School of ...
Tsunoda Y, Sasaki A, Sakamoto N, Teraoka K, Nakagawa R, Koshida Y, Fukuma E   +6 more
doaj  

Genomic Analysis of LEA Genes in Carica papaya and Insight into Lineage-Specific Family Evolution in Brassicales

Life, 2022
Late embryogenesis abundant (LEA) proteins comprise a diverse superfamily involved in plant development and stress responses. This study presents a first genome-wide analysis of LEA genes in papaya (Carica papaya L., Caricaceae), an economically ...
Zhi Zou, Jingyuan Guo, Yujiao Zheng, Yanhua Xiao, Anping Guo   +4 more
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

TabsPBP2, a Pheromone-Binding Protein Highly Expressed in Male Antennae of Tuta absoluta, Binds Sex Pheromones and Tomato Volatiles

Biomolecules
The tomato leafminer (Tuta absoluta), a globally invasive pest, poses a major economic threat to tomato production. Although chemical control remains the primary management method, sustainable alternatives are urgently needed. Sex pheromone communication
Cheng Qu, Jingxue Yan, Zuqing Yan, Ren Li, Yuqi Liu, Aoli Lin, Yuejun Fu, Chen Luo, Zhiwei Kang, Ran Wang   +9 more
doaj   +1 more source

Prostate-Derived Ets Transcription Factor Overexpression is Associated with Nodal Metastasis, Hormone Receptor Positivity in Invasive Breast Cancer

Neoplasia: An International Journal for Oncology Research, 2007
Prostate-derived Ets transcription factor (PDEF) has recently been associated with invasive breast cancer, but no expression profile has been defined in clinical specimens.
Simon Turcotte, Marie-Andree Forget, Diane Beauseigle, Edgar Nassif, Rejean Lapointe   +4 more
doaj   +1 more source

Micro-RNA expression profile of chicken small intestines during Eimeria necatrix infection

Poultry Science, 2020
Eimeria necatrix is a high pathogenic pathogen second to Eimeria tenella causing chicken coccidiosis. However, the precise underlying molecular mechanisms of interaction between E. necatrix and chickens are not fully understood.
Ting-Li Liu, Xian-Cheng Fan, Yi Wang, Yu-Xin Wang, Jun-Wei Wang, Jun-Ke Song, Guang-Hui Zhao   +6 more
doaj   +1 more source

Genome-Wide Characterization of Glutamine Synthetase Family Genes in Cucurbitaceae and Their Potential Roles in Cold Response and Rootstock-Scion Signaling Communication

Agriculture, 2021
Glutamine synthetase (GS; EC 6.3.1.2, L-glutamate: ammonia ligase ADP-forming) is the key enzyme responsible for the primary assimilation and reassimilation of nitrogen (N) in higher plants.
Xiaojun Li, Xiaohong Lu, Mengshuang Liu, Chenggang Xiang, Wenqian Liu, Cuicui Wang, Xiaojing Zhang, Tao Wang, Zixi Liu, Lihong Gao, Wenna Zhang   +10 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source