Results 41 to 50 of about 3,549 (259)

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

ILLOCUTIONARY ACTS OF HATE SPEECH: ANALYZING SOCIAL MEDIA COMMENTARY TARGETING ANIES BASWEDAN

open access: yesIndonesian EFL Journal
This study aimed to describe the types of illocutionary hate speech acts in social media comments. Qualitative design is conducted in this research. The technique of data collection are free listening techniques (Simak Bebas Libat Cakap) and recording ...
Fatimah Sari Siregar   +3 more
doaj   +1 more source

Tindak Tutur Ilokusi dalam Film Animasi Salahuddin Al-Ayyubi

open access: yesDiwan: Jurnal Bahasa dan Sastra Arab, 2022
This article discusses speech acts in the animated film Salahuddin al-Ayyubi. This research method is descriptive qualitative. By using the method of listening and recording the data in the form of words and sentences in this film were collected and ...
Erip Primadani
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Analyzing Expressive Speech Acts in The Late Late Show with James Corden

open access: yesInspiring
The Late Late program with James Corden, a prominent late-night talk program, is a great resource for studying expressive speech acts. This study aims to analyze the types of expressive speech acts performed by James Corden in The Late Late Show with ...
Nazrah, Ana Rosida
doaj   +1 more source

Tindak Tutur Ekspresif dalam Lirik Lagu Arab Populer: Analisis Lagu Magadir dan Nur Al-‘Ain

open access: yesDiwan: Jurnal Bahasa dan Sastra Arab, 2020
This article aims to describe the function of expressive speech acts in the lyrics of popular Arabic songs. The lyrics of the Magadir song sung by Talal Maddah and Nur Al-'Ain, sung by Amru Diab, were used as data sources.
Awliya Rahmi   +2 more
doaj   +1 more source

AN ANALYSIS OF THE EXPRESSIVE SPEECH ACTS IN “THE WILLOUGHBYS” MOVIE

open access: yesJURNAL BASIS, 2023
This research focuses on identifying the expressive speech acts found in “The Willoughbys” Movie. The research uses the theory of Searle and Vanderveken (1985). The method is observation in collecting the data, and the technique is note-taking. In analyzing the data, the data was examined with the pragmatic identity method and pragmatic competence-in ...
Roby Octo Aritonang, Ambalegin Ambalegin
openaire   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

Model Pertuturan Anak Down Syndrome SMA Luar Biasa Dian Grahita Jakarta: Kajian Pragmatik

open access: yesDiglosia, 2021
This study aimed to identify and describe the speech model for children with down syndrome in Dian Grahita Special High School Jakarta with a pragmatic study. This research is qualitative. The subjects in this study were Dian Grahita Special High School
Wini Tarmini   +2 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

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