Results 171 to 180 of about 47,555 (189)

PERFECTA Loaded Lipid Cubosomes for 19F‐MRI: Physico‐Chemical Characterization

open access: yesChemistry – A European Journal, EarlyView.
Phytantriol‐based cubosomes loaded with PERFCTA, a fluorinated MRI probe, were developed as promising systems for imaging and drug delivery. The nanoparticles showed high PERFECTA encapsulation efficiency, strong fluorine MRI signals, and optimal colloidal stability in biological media.
Pietro Milesi   +10 more
wiley   +1 more source

Modulation of Epigenetic Control by Advanced Molecular Tweezers

open access: yesChemistry – A European Journal, EarlyView.
Tailored dimeric molecular tweezers recognize the DNA‐binding part of Histone H4 and interrupt the essential histone‐DNA interaction. ABSTRACT This work addresses the question if supramolecular systems can be tailored to interfere with posttranslational modifications (PTM) and epigenetics.
My‐Hue‐Le   +9 more
wiley   +1 more source

Development of a Mechanically Regenerating Desublimator for Freeze‐Drying Systems in the Food Industry

open access: yesChemie Ingenieur Technik, EarlyView.
Thermal defrosting limits desublimator efficiency in freeze‐drying. This review and case study compares thermal versus mechanical regeneration, links frost properties and external heat transfer to energy demand, and summarizes pilot‐scale scraping results enabling single‐unit, continuous lyophilization.
Moritz Krummenacher   +3 more
wiley   +1 more source

Labeling Strategies for Monitoring Cytoskeleton Dynamics in Cultured Epithelial Cells

open access: yesCytoskeleton, EarlyView.
ABSTRACT Collective cell migration relies on coordinated cytoskeletal remodeling, yet the impact of live‐cell actin filament probes on these dynamics remains poorly characterized. Here, we systematically compared the performance and cellular effects of fluorogenic jasplakinolide‐based probes, SiR‐actin and SiR‐XActin, with the genetically encoded ...
Victoria Levario‐Diaz   +6 more
wiley   +1 more source

Ileal bile acid transporter inhibitors for chronic constipation in the elderly. [PDF]

open access: yesWorld J Gastrointest Pharmacol Ther
Aneesh PSR   +4 more
europepmc   +1 more source

Effect of Magnetic Islands on Neoclassical Heat Diffusivity in a Global Tokamak Simulation

open access: yesContributions to Plasma Physics, EarlyView.
ABSTRACT Resonant magnetic perturbations (RMPs) alter magnetic field topology via island formation and can modify core transport in toroidal fusion devices. Using the global gyrokinetic particle‐in‐cell code XGC‐S, originally developed for stellarator geometries, we quantify how island topology affects neoclassical heat transport in a circular tokamak ...
Joseph X. Li   +5 more
wiley   +1 more source

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