From 'quarterback' to 'coach': the policy implications of family physicians' evolving role in team-based care. [PDF]
Leslie M, McDonald A.
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Syndecans, Exostosins and Sulfotransferases as Potential Synovial Inflammation Moderators in Patients with Hip Osteoarthritis. [PDF]
Rošin M +8 more
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Donor-derived membranous nephropathy in the allograft kidney: A rare but probably underestimated complication. [PDF]
Nuccitelli RA +5 more
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Contributions of associative and non-associative learning to the dynamics of defensive ethograms. [PDF]
Le QE +6 more
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Cell surface ribonucleoproteins cluster with heparan sulfate to regulate growth factor signaling
Chai P +8 more
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Mutations in the EXT1 and EXT2 Genes in Hereditary Multiple Exostoses [PDF]
Hereditary multiple exostoses (EXT; MIM 133700) is an autosomal dominant bone disorder characterized by the presence of multiple benign cartilage-capped tumors (exostoses). Besides suffering complications caused by the pressure of these exostoses on the surrounding tissues, EXT patients are at an increased risk for malignant chondrosarcoma, which may ...
Wim Wuyts, Wim Van Hul, Egbert Bakker
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Contribution of EXT1, EXT2, and EXTL3 to Heparan Sulfate Chain Elongation [PDF]
The exostosin (EXT) family of genes encodes glycosyltransferases involved in heparan sulfate biosynthesis. Five human members of this family have been cloned to date: EXT1, EXT2, EXTL1, EXTL2, and EXTL3. EXT1 and EXT2 are believed to form a Golgi-located hetero-oligomeric complex that catalyzes the chain elongation step in heparan sulfate biosynthesis,
Jenny Presto +2 more
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Methylation status of EXT1 and EXT2 promoters and two mutations of EXT2 in chondrosarcoma
Cancer Genetics and Cytogenetics, 2005Germline mutation and functional loss of EXT1 or EXT2 are commonly found in multiple osteochondromas and predispose to the development of chondrosarcoma. Mutations of EXT1 and EXT2 have rarely been detected in sporadic secondary chondrosarcomas from osteochondroma; these frequently display loss of heterozygosity at the EXT1 and EXT2 loci, but primary ...
Takashi, Tsuchiya +16 more
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Solid State Disks (SSDs) start to replace rotating media (hard disks, HDD) in many areas, but are still not as cost efficient concerning capacity to completely replace them. One approach to use their superior performance properties is to use them as a cache for magnetic disks to speed up overall storage operations.
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