Results 171 to 180 of about 251,489 (270)

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

An atlas of exposome-phenome associations in health and disease risk. [PDF]

Nat Med
Patel CJ, Ioannidis JPA, Manrai AK.
europepmc   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Plasticity and language in the anaesthetized human hippocampus. [PDF]

Nature
Katlowitz KA, Cole ER, Mickiewicz EA, Shah S, Franch M, Adkinson JA, Belanger JL, Mathura RK, Meszéna D, McGinley M, Muñoz W, Banks GP, Cash SS, Hsu CW, Paulk AC, Provenza NR, Watrous AJ, Williams Z, Goldman AM, Krishnan V, Maheshwari A, Heilbronner SR, Kim R, Rungratsameetaweemana N, Hayden BY, Sheth SA.   +25 more
europepmc   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

FEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

Dynamical study of optical soliton solutions to the Lakshmanan-Porsezian-Daniel equation by using [Formula: see text]-model expansion approach. [PDF]

Sci Rep
Alharthi MR, Inayat M, Abbas M, Birhanu A, Yousaf MZ, El-Zahar ER.   +5 more
europepmc   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Post-OGTT hypoglycaemia in newly diagnosed type 2 diabetes: frequency, characteristics and cluster assignment. [PDF]

Diabetologia
Spies R, Ufer G, Sabia R, Hummel J, Peter A, Wagner R, Heni M.   +6 more
europepmc   +1 more source

Some generalized inequalities involving extended beta and gamma functions for several variables

Recently, extensions of gamma and beta functions have been studied by many researchers due to their nice properties and variety of applications in different fields of science.
Mubeen, S., Khammash, Ghazi S., Shehata, Ayman, Aslam, I., Nadarajah, Saralees   +4 more
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