Results 111 to 120 of about 683,134 (295)

Landscape of BRAF transcript variants in human cancer

open access: yesMolecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda   +5 more
wiley   +1 more source

TRPM8 levels determine tumor vulnerability to channel agonists

open access: yesMolecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo   +18 more
wiley   +1 more source

The acceptability of participating in data linkage research: research with older Australians

open access: yesAustralian and New Zealand Journal of Public Health, 2018
Stephanie L. Harrison   +4 more
doaj   +1 more source

Effect of extended care APPs based on the transtheoretical model of behavior change on self-management abilities in young and middle-aged patients with newly diagnosed diabetes mellitus (基于行为转变理论的APP延续护理模式对初诊中青年糖尿病患者自我管理能力的影响)

open access: yes中西医结合护理
Objective To investigate the effect of extended care APPs based on the transtheoretical model of behavior change on indexes of glucose metabolism and self-management abilities in young and middle-aged patients with newly diagnosed diabetes mellitus ...
YANG Yongfang (杨永芳)   +1 more
doaj   +1 more source

Implementing a Resident Lifting System in an Extended Care Hospital [PDF]

open access: bronze, 2002
Jerry Spiegel   +5 more
openalex   +1 more source

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

open access: yesMolecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton   +17 more
wiley   +1 more source

Application of Internet Plus nursing services in the management of chronic diseases among the elderly (“互联网+护理服务”在老年慢性病患者管理中的应用)

open access: yes中西医结合护理
With the increasingly significant aging trend of China's population, the number of patients with chronic diseases is constantly rising, and the characteristics of chronic diseases determine that most of the treatment and rehabilitation time is spent in ...
LI Jiao (李娇)   +1 more
doaj   +1 more source

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