Results 111 to 120 of about 831,260 (309)

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Missing Work and Quitting Work: Child Care-Related Employment Problems [PDF]

open access: yes
Qualitative research points to logistical problems in coordinating child care as a key obstacle to maternal employment for low-income mothers. But quantitative research has largely overlooked this everyday aspect of combining work and family.
Douglas A. Wolf, Margaret L. Usdansky
core  

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Nursing of a patient with severe kyphotic deformity undergoing staged surgical treatment (1例重度脊柱后凸畸形患者分期矫形围术期护理体会)

open access: yes中西医结合护理
This paper summarized the nursing experience of a patient with ankylosing spondylitis complicated with severe kyphotic deformity and orthopaedic surgery in 3 stages, focusing on the management of respiratory system, intraoperative bleeding, blood ...
LI Benhua (李本花)   +6 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Investigation on extended care needs of patients with hypertensive intracerebral hemorrhage (高血压性脑出血患者延续性护理服务需求调查)

open access: yes中西医结合护理
Objective To understand the extended care needs of patients with hypertensive intracerebral hemorrhage, investigate the construction methods of extended nursing service and provide reference for clinical nursing practice of hypertensive intracerebral ...
QIU Yajiao (邱亚娇)   +2 more
doaj   +1 more source

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