Results 121 to 130 of about 496,006 (293)
FEBS Open Bio, EarlyView.We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
wiley +1 more source
Theory, practice and performance
Connection Science, 2017 I focus on the enactivist and extended mind approaches to embodied cognition (EC), and specifically on the concepts of body schema, affectivity, distributed cognition and intersubjectivity to show how EC has relevance to questions about expert ...
Shaun Gallagher
doaj +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Bioethics and the Hypothesis of Extended Health [PDF]
, 2018 Dominant views about the nature of health and disease in bioethics and the philosophy of medicine have presumed the existence of a fixed, stable, individual organism as the bearer of health and disease states, and as such, the appropriate target of ...
Morar, Nicolae, Skorburg, Joshua August
core
FEBS Open Bio, EarlyView.ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand +2 more
wiley +1 more source
Memory, Mind & MediaThis paper offers a systematic and interdisciplinary analysis of contemporary work on memory externalization, with a particular focus on how technological systems are integrated into human mnemonic practices.
Nicolas Crozatier
doaj +1 more source
Emotion and Cognition: Recent developments and Therapeutic Practice [PDF]
As is widely known, the last twenty-five years have seen an acceleration in the development of theories of emotion. Perhaps less well-known is that the last three years have seen an extended defense of a predominant, although not universally accepted ...
Lacewing, Michael
core
Scientia intuitiva in the Ethics [PDF]
, 2017 **For my more recent views of the third kind of cognition, see my "Finding Oneself in God"** Abstract: Cognition of the third kind, or scientia intuitiva, is supposed to secure beatitudo, or virtue itself (E5p42).
Primus, Kristin
core
Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells
FEBS Open Bio, EarlyView.Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi +7 more
wiley +1 more source