Results 131 to 140 of about 113,287 (282)

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Artificial intelligence, extended cognition, and the narratives of cyberimmortality

Filosofia Unisinos
The article shows how the extended mind theory, which suggests that cognition is not confined to the brain but extends beyond the body, is used to redefine our understanding of the nature of the mind and legitimize narratives of cyberimmortality ...
Léo Peruzzo Júnior
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

PRAGMATIC INTERVENTIONS INTO ENACTIVE AND EXTENDED CONCEPTIONS OF COGNITION

, 2014
Clear statements of both extended and enactive conceptions of cognition can be found in John Dewey and other pragmatists. In this paper I\u27ll argue that we can find resources in the pragmatists to address two ongoing debates: (1) in contrast to recent ...
Gallagher, Shaun, Shaun Gallagher
core   +1 more source

Autopoiesis + extended cognition + nature = can buildings think? [PDF]

Commun Integr Biol, 2015
Dollens D.
europepmc   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

How to go beyond the body: An introduction

Frontiers in Psychology, 2015
Guy eDove
doaj   +1 more source

Exploring Human-Tech Hybridity at the Intersection of Extended Cognition and Distributed Agency: A Focus on Self-Tracking Devices. [PDF]

Front Psychol, 2018
Duus R, Cooray M, Page NC.
europepmc   +1 more source

Intelligent Tutoring Systems for Adult Learning in STEM Disciplines

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Intelligent tutoring systems (ITS) are reshaping adult learning in STEM by providing adaptive, data‐driven instruction across classrooms, workplaces, and informal environments. In the context of ITS, this article compares generative AI, which creates personalized explanations and practice materials, with explainable AI, which focuses on ...
Jill Zarestky, Amanda R. Lager Gleason
wiley   +1 more source