Results 31 to 40 of about 212,453 (210)
A sufficient condition to extend polynomial results for the Maximum Independent Set Problem
Discrete Applied Mathematics, 2017 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +3 more sources
Conditional Probability and Conditional Expectation of a Multivariate Normal Random Variable Over a Rectangle [PDF]
, 1984 The idea of orthonormal variates, designed by Deak to find conditional probabilities of a multivariate normal random variable, is extended to compute the conditional expectation given that the observation falls inside an n-dimensional rectangle.
Gassmann, H.I.
core
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Developmental, Neuroanatomical and Cellular Expression of Genes Causing Dystonia
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Dystonia is one of the most common movement disorders, with variants in multiple genes identified as causative. However, an understanding of which developmental stages, brain regions, and cell types are most relevant is crucial for developing relevant disease models and therapeutics.
Darren Cameron +5 more
wiley +1 more source
Bayesian Decision Theory and Stochastic Independence [PDF]
, 2020 As stochastic independence is essential to the mathematical development of probability theory, it seems that any foundational work on probability should be able to account for this property. Bayesian decision theory appears to be wanting in this respect.
Mongin, Philippe
core
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane +43 more
wiley +1 more source
Comparison of Parametric Rate Models for Gap Times Between Recurrent Events
MathematicsOver the past two decades, substantial efforts have been made to develop survival models for gap times between recurrent events. An emerging approach involves considering rate models derived from a non-homogeneous Poisson process, thus allowing the ...
Ivo Sousa-Ferreira +2 more
doaj +1 more source
ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
The matching polytope does not admit fully-polynomial size relaxation schemes
, 2015 The groundbreaking work of Rothvo{\ss} [arxiv:1311.2369] established that every linear program expressing the matching polytope has an exponential number of inequalities (formally, the matching polytope has exponential extension complexity).
Braun, Gábor, Pokutta, Sebastian
core +1 more source
Advanced Engineering Materials, EarlyView.Viktoriia Shtefan, Thorgund Nemec, Ute Hempel, Annett Gebert and coworkers demonstrate that anodic treatment of Ti–Cu‐based metallic glass in a nontoxic pyrophosphate electrolyte forms a protective bilayered Ti/Zr‐oxide film enriched with Cu nanocrystals.
Viktoriia Shtefan +8 more
wiley +1 more source