Results 131 to 140 of about 6,414,954 (167)

Mitochondrial metabolism and epigenetic crosstalk drive SASP. [PDF]

Nature
Martini H, Birch J, Marques FDM, Victorelli S, Lagnado AB, Pirius N, Franco AC, Lee G, Han Y, Rowsey JL, Ismail WM, Mazzone A, Espe TM, Hitosugi T, Li Y, Washington AM, Havas A, Murad R, Lei X, Porritt RA, Maddocks ODK, Machado Espindola-Netto J, Saul D, Khosla S, Jurk D, Kostallari E, Gaspar-Maia A, Adams PD, Passos JF.   +28 more
europepmc   +1 more source

Targeting immunometabolic pathways with AZD1656 alleviates inflammation and metabolic dysfunction in type 2 diabetic cardiomyopathy. [PDF]

Nat Cardiovasc Res
Anderson S, Karlstaedt A, Young M, Karatzia L, Cullen F, Chen J, O'Riordan CE, Barnes MR, Štaka Z, Albee LJ, Garrod-Ketchley C, Dambure S, Prag HA, Cvetko F, Miller JJJJ, Thiemermann C, Lewis AJM, Murphy MP, Smith DM, Henson SM, Tyler DJ, Aksentijevic D.   +21 more
europepmc   +1 more source

Blood methylome signatures in children exposed to maternal type 1 diabetes are linked to protection against islet autoimmunity. [PDF]

Nat Metab
Ott R, Zapardiel-Gonzalo J, Kreitmaier P, Casteels K, Hommel A, Kordonouri O, Elding Larsson H, Szypowska A, Vatish M, Zeggini E, Knopff A, Winkler C, Ziegler AG, Bonifacio E, Hummel S.   +14 more
europepmc   +1 more source

Pangenome-resolved structural variation drives adaptation and trait evolution in cucumber. [PDF]

Nat Genet
Guan J, Li X, Miao H, Yan X, Liu X, Gu X, Visser RGF, Bai Y, Huang S, Zhang Z, Dong S, Zhang S.   +11 more
europepmc   +1 more source

Lamin A/C-regulated cysteine catabolic flux modulates stem cell fate through epigenome reprogramming. [PDF]

Nat Metab
Wang Y, Shi H, Wittig J, Ren Y, Cordero J, Dewenter M, Mella J, Buchwalter A, Backs J, Wieland T, Heineke J, Fleming I, Bibli SI, Dobreva G.   +13 more
europepmc   +1 more source

Cell-specific DNA methylation in human alpha and beta cells regulates gene expression in type 2 diabetes. [PDF]

Nat Metab
Ofori JK, Ruhrmann S, Lindström A, Perfilyev A, Martin M, Karagiannopoulos A, Scisciola L, Kost K, Jönsson J, Nilsson Å, Kantor B, Dudenhöffer-Pfeifer M, Rots MG, Wendt A, Rönn T, Eliasson L, Bacos K, Ling C.   +17 more
europepmc   +1 more source

SpaMTP: integrative statistical analysis and visualization of spatial metabolomics and transcriptomics data. [PDF]

Nat Methods
Causer A, Lu T, Kriel J, Moffet JJD, Fitzgerald CCJ, Newman A, Vu H, Tan X, Vo T, Cui C, Narayana VK, Whittle JR, Best SA, Freytag S, Nguyen Q.   +14 more
europepmc   +1 more source

EHE cell cultures are a platform for mechanistic and therapeutic investigation. [PDF]

Sci Rep
Scalora N, DeWane G, Drebot Y, Khan AA, Sinha S, Ghosh K, Robinson D, Cogswell P, Bellizzi AM, Snow AN, Breheny P, Chimenti MS, Tanas MR.   +12 more
europepmc   +1 more source

Repeated head trauma causes neuron loss and inflammation in young athletes. [PDF]

Nature
Butler MLMD, Pervaiz N, Breen K, Calderazzo S, Ypsilantis P, Wang Y, Breda JC, Mazzilli S, Nicks R, Spurlock E, Hefti MM, Fiock KL, Huber BR, Alvarez VE, Stein TD, Campbell JD, McKee AC, Cherry JD.   +17 more
europepmc   +1 more source

Intracellular iron homeostasis-regulated epigenetic reprogramming contributes to -7/del(7q) leukemia. [PDF]

Nat Commun
Zheng J, Peng Y, Deng X, Zhang L, Wang Z, Chen X, Li H, Li Y, Zhang Q, Zheng L, Qi Z, Wang L, Lu M, Cui W, Wang L, Wu Y, Zhao W, Niu T, Chen C, Liu Y.   +19 more
europepmc   +1 more source