Results 161 to 170 of about 40,608 (254)

Multi-tissue transcriptomic aging atlas reveals predictive aging biomarkers in the killifish. [PDF]

Nat Aging
Costa EK, Chen J, Guldner IH, Mboning L, Schmahl N, Tsenter A, Nagvekar R, Wu MR, Moran-Losada P, Bouchard LS, Wang S, Singh PP, Pellegrini M, Brunet A, Wyss-Coray T.   +14 more
europepmc   +1 more source

Deletion of a Pax1 Sex‐Associated Genomic Region Associated With Adolescent Idiopathic Scoliosis Leads to Disc Degeneration, Instability, and Vertebral Rotation in Mice

JOR SPINE, Volume 9, Issue 2, June 2026.
Overview of the effects of Pax1‐SAR deletion on gene expression, IVD degeneration, and resultant scoliotic‐like curvature between sexes. Proposed mechanism of sex‐dependent changes in gene expression in females (right) and males (left), resulting in sex‐dependent disc degeneration and scoliotic phenotypes.
Edward C. Moody, Emma M. Wade, Shuji Mizumoto, Jeremy McCallum‐Loudeac, Megan J. Wilson   +4 more
wiley   +1 more source

Single-cell spatiotemporal transcriptomic and chromatin accessibility profiling in developing postnatal human and macaque prefrontal cortex. [PDF]

Nat Neurosci
Zhang J, Li M, Wang M, Sun Y, Yin C, Yang S, Wang B, Liu Z, Wang W, Liu M, Zhao Y, Zhou X, Cai L, Zhong S, Wang X, Wu Q.   +15 more
europepmc   +1 more source

Genetic architecture of angular leaf spot resistance in cultivated strawberry shaped by epistasis and genotype‐by‐environment interactions

The Plant Genome, Volume 19, Issue 2, June 2026.
Abstract Angular leaf spot (ALS), caused by Xanthomonas fragariae, is a bacterial disease that limits strawberry (Fragaria × ananassa) productivity worldwide. Although major resistance loci have been identified in wild Fragaria species, their introgression into elite germplasm remains constrained by linkage drag and inconsistent inheritance. To dissect
Shai Torgeman, Dominique D. A. Pincot, Marta Bjornson, Randi A. Famula, Paul Skillin, Allison Krill‐Brown, Mitchell J. Feldmann   +6 more
wiley   +1 more source

Explicit minimisers for anisotropic Riesz energies. [PDF]

Calc Var Partial Differ Equ
Frank RL, Mateu J, Mora MG, Rondi L, Scardia L, Verdera J.   +5 more
europepmc   +1 more source

Proteomic Profiling of Plasma to Uncover Novel Intervention Targets and Prognostic Biomarkers for Chronic Liver Diseases

Diabetes, Obesity and Metabolism, Volume 28, Issue 6, Page 5029-5042, June 2026.
ABSTRACT Aims The burden of chronic liver disease (CLD) is increasing. This study aims to identify protein markers for CLD and its progression, and develop a protein‐based risk prediction model. Materials and Methods We used proteome‐wide Mendelian randomization (MR), Bayesian colocalization and summary‐data‐based MR with proteomic data from deCODE ...
Xinxuan Li, Jing Sun, Jianhui Zhao, Fangyuan Jiang, Meng Zhang, Hao Wu, Shuai Yuan, Xue Li, Juan Lu, Christos S. Mantzoros   +9 more
wiley   +1 more source

Immune dysregulation triggered by inflammatory cytokines in patients with severe respiratory infections. [PDF]

Respir Res
Li J, Liang S, Li Y, Wu J, Li C, Gan J, Li W, Wang C.   +7 more
europepmc   +1 more source

Transcriptomic analysis reveals the hepatic response mechanisms of the Chinese spiny frog (Quasipaa spinosa) to Citrobacter freundii infection

Journal of the World Aquaculture Society, Volume 57, Issue 3, June 2026.
Abstract To elucidate the pathogen and host response mechanisms underlying mass mortality in Quasipaa spinosa, dominant bacteria were isolated from diseased individuals and identified as Citrobacter freundii by morphological, physiological, and biochemical characterization, 16S rRNA sequencing, and phylogenetic analysis.
Yanhong Li, Baohong Zhou, Yiran Lu, Yi Zang, Minghao Hu, Qiaochen Jin, Wenbin Fang, Shanjian Zheng   +7 more
wiley   +1 more source

Benzoxazinoid‐mediated microbiome feedbacks enhance Arabidopsis growth and defence

New Phytologist, Volume 250, Issue 5, Page 3334-3348, June 2026.
Summary Plants modulate their surrounding microbiome via root exudates and such conditioned soil microbiomes feed back on the performance of the next generation of plants. How plants perceive altered soil microbiomes and modulate their performance in response to such microbiome feedbacks, however, remains largely unknown.
Katja Stengele, Lea Stauber, Lisa Thoenen, Henry Janse van Rensburg, Viola D'Adda, Klaus Schlaeppi   +5 more
wiley   +1 more source

Targeting immunometabolic pathways with AZD1656 alleviates inflammation and metabolic dysfunction in type 2 diabetic cardiomyopathy. [PDF]

Nat Cardiovasc Res
Anderson S, Karlstaedt A, Young M, Karatzia L, Cullen F, Chen J, O'Riordan CE, Barnes MR, Štaka Z, Albee LJ, Garrod-Ketchley C, Dambure S, Prag HA, Cvetko F, Miller JJJJ, Thiemermann C, Lewis AJM, Murphy MP, Smith DM, Henson SM, Tyler DJ, Aksentijevic D.   +21 more
europepmc   +1 more source