Results 171 to 180 of about 40,608 (254)

Phosphate starvation induces root cell‐type‐specific transcriptional responses and alternative splicing

New Phytologist, Volume 250, Issue 5, Page 3212-3229, June 2026.
Summary Phosphate (Pi) is an essential nutrient for plant growth, and understanding how Arabidopsis thaliana root cells respond to Pi deficiency is crucial to decipher whole plant responses. We perform high‐resolution transcriptomic profiling across five distinct root cell types, identifying differentially expressed genes (DEGs) and differential ...
Mary‐Paz González‐García, Mónica Lanza, Victoria Baca‐González, Estefano Bustillo‐Avendaño, Laura Serrano‐Ron, Sara González‐Bodi, Jose M. García‐Mina, Ángel M. Zamarreño, María Garnica, Miguel A. Moreno‐Risueno, Elena Caro, Juan C. del Pozo   +11 more
wiley   +1 more source

Lamin A/C-regulated cysteine catabolic flux modulates stem cell fate through epigenome reprogramming. [PDF]

Nat Metab
Wang Y, Shi H, Wittig J, Ren Y, Cordero J, Dewenter M, Mella J, Buchwalter A, Backs J, Wieland T, Heineke J, Fleming I, Bibli SI, Dobreva G.   +13 more
europepmc   +1 more source

The abundance of pollen coat small signaling proteins shows limited convergence between independent selfing transitions in Arabidopsis and Capsella

New Phytologist, Volume 250, Issue 5, Page 3460-3474, June 2026.
Summary In plants, a key example of convergence is the repeated evolution of floral traits associated with the transition from outcrossing to self‐fertilization, often resulting in the ‘selfing syndrome’ (e.g. reduced flower size and loss of scent). However, potentially overlooked changes concern the pollen coat, which plays a role in different aspects
Ömer İltaş, Luciana Salomon, Martin Kovačik, Martin Čertner, Pavel Talacko, Karel Harant, Said Hafidh, Clément Lafon Placette   +7 more
wiley   +1 more source

Blood methylome signatures in children exposed to maternal type 1 diabetes are linked to protection against islet autoimmunity. [PDF]

Nat Metab
Ott R, Zapardiel-Gonzalo J, Kreitmaier P, Casteels K, Hommel A, Kordonouri O, Elding Larsson H, Szypowska A, Vatish M, Zeggini E, Knopff A, Winkler C, Ziegler AG, Bonifacio E, Hummel S.   +14 more
europepmc   +1 more source

GENERATING FUNCTIONS FOR THE EXTENDED WRIGHT TYPE HYPERGEOMETRIC FUNCTION

Communications of the Korean Mathematical Society, 2017
Ranjan Kumar Jana, Bhumika Maheshwari, Ajay Kumar Shukla   +2 more
openaire   +2 more sources

Pancancer Fine‐Mapping of Mutational Intolerance Identifies CHEK1 as an Immunosuppressive Driver in Lung Adenocarcinoma

Advanced Science, Volume 13, Issue 25, 4 May 2026.
This study identifies mutation‐intolerant genes (MIGs), which are mutationally constrained in tumors despite normal‐tissue variability. Using miDriver, the authors pinpoint MIGs essential for tumor‐intrinsic fitness and immune evasion. Focusing on CHEK1, they show it drives tumor fitness and sculpts an immunosuppressive niche via the MIF–CD74 axis ...
Tao Wang, Hongyu Zhao, Xiaojie Sun, Yuqi Ding, Zhipeng Zhu, Xiaotong Yu, Rongyi Zhu, Dan Wang, Kailong Li, Yang Liu, Li‐Bin Wang, Xiaolu Zhao, Baojun Suo, Hongsen Bi, Peipei Zhang, Tong Liu, Fengbiao Mao   +16 more
wiley   +1 more source

EHE cell cultures are a platform for mechanistic and therapeutic investigation. [PDF]

Sci Rep
Scalora N, DeWane G, Drebot Y, Khan AA, Sinha S, Ghosh K, Robinson D, Cogswell P, Bellizzi AM, Snow AN, Breheny P, Chimenti MS, Tanas MR.   +12 more
europepmc   +1 more source

Safety and Feasibility of a CT‐Based Pathway for Left Atrial Appendage Assessment Prior to Inpatient Cardioversion: A Single‐Center Experience

Clinical Cardiology, Volume 49, Issue 5, May 2026.
An alternative for TEE? Cardiac CT is a practical alternative for ruling out LA/LAA thrombi in hospitalized patients who need cardioversion. ABSTRACT Background Transesophageal echocardiography (TEE) for left atrial appendage (LAA) thrombus exclusion before cardioversion faces logistical barriers including limited availability, patient intolerance, and
Ariel Furer, Maxim Perelman, Yafim Brodov, Orly Goitein, Sagit Ben Zikri, Rafael Kuperstein, Edward Itelman, Elad Maor, Eyal Nof, Roy Beinart, Shlomi Matetzky, Roy Beigel   +11 more
wiley   +1 more source

Transcriptome- and phenotype-based epistasis analysis in Caenorhabditis elegans reveals daf-16/FoxO-dependent and independent effects of daf-2/InsR in L1 starvation and recovery. [PDF]

G3 (Bethesda)
Fisher K, Chitrakar R, Baugh LR.
europepmc   +1 more source

Oncogenic driver and therapeutic target: Prolactin signalling axis in retroperitoneal sarcoma

Clinical and Translational Medicine, Volume 16, Issue 5, May 2026.
Retroperitoneal sarcoma cells can secrete prolactin into the bloodstream, inducing hyperprolactinaemia, which subsequently triggers metabolic reprogramming, such as glucose metabolism. SOX4 can function as a transcription factor that facilitates PRL transcription.
Fu'an Xie, Lingwei Gu, Kunrong Yang, Shuai Wang, Mengmeng Xiao, Guangting Yan, Quan Zhang, Rubing Liang, Aobo Zhuang, Zhe Xi, Yujia Niu, Yanhua Chen, Xiaogang Xia, Linlin Qu, Bin Zhao, Weibing Li, Ting Wu, Chundong Yu, Chenghua Luo, Houzhao Wang, Lanlan Lian, Wengang Li   +21 more
wiley   +1 more source