Results 221 to 230 of about 38,609 (257)

Extended-interval Aminoglycoside Dosing in Pediatrics

Pediatric Infectious Disease Journal, 2011
Aminoglycosides (AGs) are often used in combination with -lactam antibiotics for the treatment of serious Gram-negative infections. Traditionally, AGs have been dosed multiple times a day. Over the past decade, extended-interval dosing has been evaluated as a method of improving the efficacy and safety of AGs.
Alice M, Jenh, Pranita D, Tamma, Aaron M, Milstone   +2 more
openaire   +2 more sources

Natalizumab extended-interval dosing in a real-life setting

Journal of the Neurological Sciences, 2023
Natalizumab is a high-efficacy therapy for recurrent multiple sclerosis (RMS) with a four-week administration interval. Controlled trials have shown that extending this interval to six weeks led to better safety without increasing the risk of relapse. We aimed to analyze the safety of extending the natalizumab interdose interval from 4 to 6 weeks in a ...
Lina, Jeantin, Marine, Boudot de la Motte, Romain, Deschamps, Antoine, Gueguen, Olivier, Gout, Augustin, Lecler, Caroline, Papeix, Caroline, Bensa   +7 more
openaire   +2 more sources

Atorvastatin: Extended-Interval Dosing

Hospital Pharmacy, 2011
This Hospital Pharmacy feature is extracted from Off-Label Drug Facts, a quarterly publication available from Wolters Kluwer Health. Off-Label Drug Facts is a practitioner-oriented resource for information about specific drug uses that are unapproved by the US Food and Drug Administration.
Joyce A. Generali, Dennis J. Cada
openaire   +1 more source

Rosuvastatin: Extended-Interval Dosing

Hospital Pharmacy, 2011
This Hospital Pharmacy feature is extracted from Off-Label Drug Pacts, a quarterly publication available from Wolters Kluwer Health. Off-Label Drug Pacts is a practitioner-oriented resource for information about specific drug uses that are unapproved by the US Food and Drug Administration.
A. Generali Joyce, J. Cada Dennis
openaire   +1 more source

National Survey of Extended-Interval Aminoglycoside Dosing

Clinical Infectious Diseases, 2000
A random sample survey of 500 acute care hospitals in the United States was conducted to evaluate the adoption of extended-interval aminoglycoside dosing (EIAD). The survey revealed that EIAD has been adopted in 3 of every 4 acute care hospitals, a 4-fold increase since 1993. Of the 74.7% of hospitals reporting EIAD, 64% had written guidelines.
S K, Chuck, S R, Raber, K A, Rodvold, D, Areff   +3 more
openaire   +2 more sources

Extended interval dosing of natalizumab in multiple sclerosis

Journal of Neurology, Neurosurgery & Psychiatry, 2016
Natalizumab (NTZ), a monoclonal antibody to human α4β1/β7 integrin, is an effective therapy for multiple sclerosis (MS), albeit associated with progressive multifocal leukoencephalopathy (PML). Clinicians have been extending the dose of infusions with a hypothesis of reducing PML risk.
L, Zhovtis Ryerson, T C, Frohman, J, Foley, I, Kister, B, Weinstock-Guttman, C, Tornatore, K, Pandey, S, Donnelly, S, Pawate, R, Bomprezzi, D, Smith, C, Kolb, S, Qureshi, D, Okuda, J, Kalina, Z, Rimler, R, Green, N, Monson, T, Hoyt, M, Bradshaw, J, Fallon, E, Chamot, M, Bucello, S, Beh, G, Cutter, E, Major, J, Herbert, E M, Frohman   +27 more
openaire   +2 more sources

Extended Interval Dosing of Gentamicin in Preterm Infants

American Journal of Perinatology, 2004
Conventional interval dosing (CID) and extended interval dosing (EID) of gentamicin were compared in preterm infants. Gentamicin peak and trough levels, serum creatinine, urine output, and hearing screens were obtained in 40 preterm infants. Results suggest that EID is safe, provides gentamicin levels in desirable ranges (peak, 5 to 12 microg/mL ...
Ma Cecilia K, Mercado, Nancy L, Brodsky, Michael K, McGuire, Hallam, Hurt   +3 more
openaire   +2 more sources

Loading Doses and Extended Dosing Intervals in Topical Gentamicin Therapy

American Journal of Ophthalmology, 1985
Loading doses and extended dosing intervals were studied in a rabbit model using topically applied gentamicin in a concentration of 13.6 mg/ml. Loading doses consisting of one drop every minute for five minutes produced significantly higher gentamicin concentrations in the cornea during the early hours of treatment than regimens using one drop every ...
D B, Glasser, S, Gardner, J G, Ellis, T H, Pettit   +3 more
openaire   +2 more sources

Omeprazole: Extended-Interval Dosing (Alternate-Day Dosing)

Hospital Pharmacy, 2006
Off-Label Drug Uses This Hospital Pharmacy feature is extracted from Off-Label DrugFacts, a quarterly publication available from Wolters Kluwer Health. Off-Label DrugFacts is a practitioner-oriented resource for information about specific FDA-unapproved drug uses. This new guide to the literature will enable the
Joyce Generali, Dennis J. Cada
openaire   +1 more source

Influence of personalized extended interval dosing on the natalizumab wearing-off effect - a sub-study of the NEXT-MS trial [PDF]

Journal of the Neurological Sciences
Background and objectives: Wearing-off symptoms during natalizumab treatment in multiple sclerosis are characterized by an increase of MS-related symptoms prior to natalizumab administration. The influence of extended interval dosing (EID) on wearing-off
N F Kalkers, M Eurelings
exaly   +2 more sources