Results 91 to 100 of about 123,075 (256)

Prognostic Value of Neurofilament Light Chain and Glial Fibrillary Acidic Protein in ALD‐Related Myelopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background X‐linked adrenoleukodystrophy (X‐ALD) is a neurometabolic disorder caused by pathogenic variants in ABCD1, leading to slowly progressive spinal cord disease in nearly all affected men. Sensitive biomarkers to quantify disease severity and predict progression are needed for clinical care and trial design.
Eda G. Kabak   +4 more
wiley   +1 more source

Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif   +17 more
wiley   +1 more source

Lifetime progression of IgA nephropathy: a retrospective cohort study with extended long-term follow-up

open access: yesBMC Nephrology
Background IgA nephropathy (IgAN) exhibits an unpredictable trajectory, creating difficulties in prognostication, monitoring, treatment, and research planning. This study provides a comprehensive depiction of the progression of kidney function throughout
Mariell Rivedal   +5 more
doaj   +1 more source

Histopathological Evidence of Neurodegenerative Pathology in Epilepsy: A Systematic Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Epilepsy affects > 50 million people worldwide and is associated with a disproportionate burden of cognitive impairment. Emerging evidence suggests that neurodegenerative proteinopathies, particularly hyperphosphorylated tau (p‐tau) and amyloid‐β (Aβ), may contribute to cognitive dysfunction in people with epilepsy (PWE), even in the absence ...
Syeda Amrah Hashmi   +7 more
wiley   +1 more source

Active layered localization method for dynamic muti-sinks wireless sensor networks

open access: yesTongxin xuebao, 2007
An active layered localization method was proposed.The method was event-driven and divided into two layers(sensor layer and sink layer).The method not only supported the movement of nodes,but also reduced the localization cost of sensors and extended the
HAN Peng   +3 more
doaj   +2 more sources

BEES: Quasar Lifetime Measurements from Extended Rest-optical Emission Line Nebulae at z ∼ 6

open access: yesThe Astrophysical Journal
Measurements of quasar lifetimes at high redshift indicate that the earliest billion-solar-mass supermassive black holes (SMBHs) have only been active as luminous quasars for less than a million years.
Dominika Ďurovčíková   +15 more
doaj   +1 more source

Lifetime prediction of copper pillar bumps based on fatigue crack propagation

open access: yesFrontiers in Materials
2.5D package realizes the interconnection of multiple dies through Si interposers, which can greatly improve the data transmission rate between dies. However, its multi-layer structure and high package density also place higher reliability requirements ...
Yuege Zhou   +8 more
doaj   +1 more source

Formal and Informal Social Care in People With Rheumatic and Musculoskeletal Diseases: A Cross‐Sectional Multicenter Survey

open access: yesArthritis Care &Research, EarlyView.
Objective Rheumatic and musculoskeletal diseases (RMDs) are leading causes of physical disability, necessitating support with activities of daily living. This study describes social care received by patients with RMDs in two disparate regions of England: Salford (urban) and Norfolk (rural).
Mehreen Somro   +6 more
wiley   +1 more source

Cumulative Social Disadvantage and Disease Activity in Juvenile Idiopathic Arthritis: A Childhood Arthritis and Rheumatology Research Alliance Registry Study

open access: yesArthritis Care &Research, EarlyView.
Objective Social determinants of health (SDOH) contribute to juvenile idiopathic arthritis (JIA) disparities, but most studies have assessed SDOH independently rather than cumulatively across individual, family, and neighborhood levels. Using a socioecological framework, we investigated the relationship among cumulative social disadvantage ...
William Daniel Soulsby   +448 more
wiley   +1 more source

Reliability-driven clustering methodology for probabilistic forecast of environmental conditions in power electronics applications

open access: yesInternational Journal of Electrical Power & Energy Systems
Modern power systems are today characterized by an increasing utilization of the power electronics. An accurate predictions of the power electronics reliability and lifetime are crucial to avoid unforeseen power outages and maintenance costs.
Monika Sandelic   +4 more
doaj   +1 more source

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