Results 71 to 80 of about 123,075 (256)
How phagocytic cells kill bacteria: Lessons from a professional killer
FEBS Open Bio, EarlyView.How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley +1 more source
Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Aging and Cancer, EarlyView.Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
Extending the Lifetime of Sensor Networks through Adaptive Reclustering
EURASIP Journal on Wireless Communications and Networking, 2007 We analyze the lifetime of clustered sensor networks with decentralized binary detection under a physical layer quality-of-service (QoS) constraint, given by the maximum tolerable probability of decision error at the access point (AP). In order to properly model the network behavior, we consider four different distributions (exponential, uniform ...
Gianluigi Ferrari 0001, Marco Martalò
openaire +6 more sources
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Secondary cluster head based SEP in heterogeneous WSNs for IoT applications
IET CommunicationsA wireless sensor network (WSN) consists of specialized sensor nodes that perform sensing services for Internet of Things devices with limited battery power.
Arif Hossan, Jahidul Islam
doaj +1 more source
A New Real-Time and Guaranteed Lifetime Protocol in Wireless Sensor Networks
International Journal of Distributed Sensor Networks, 2014 Real-time applications are time and event critical, therefore they have strict constraint on delay, packet loss, and energy consumption in many wireless sensor networks (WSNs) scenarios, which demands the network to continue QoS operations for a ...
Babar Shah, Ki-Il Kim
doaj +1 more source
Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer
Aging and Cancer, EarlyView.Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss +12 more
wiley +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Vestibular Patient Journey: Insights From Vestibular Disorders Association (VeDA) Registry
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Vestibular symptoms impose a high burden of disability. Understanding real‐world diagnostic and treatment pathways can identify care gaps and guide interventions. We aimed to characterize symptom profiles, diagnostic trends, provider involvement, and treatment patterns in vestibular disorders.
Ali Rafati +10 more
wiley +1 more source
Ultra-stable nano-micro bubbles in a biocompatible medium for safe delivery of anti-cancer drugs
Scientific ReportsWe conducted a series of experimental investigations to generate laser-stimulated millimeter bubbles (MBs) around silver nanoparticles (AgNPs) and thoroughly examined the mechanism of bubble formation within this nanocomposite system.
Ulviye Bunyatova +3 more
doaj +1 more source