Dual priming with minocycline and photodynamic priming reprograms the pancreatic tumor microenvironment to overcome chemoresistance. By suppressing DNA repair enzyme Tdp1, inducing photooxidative damage, and enhancing irinotecan delivery via light‐activated nanoencapsulation, this strategy remodels the tumor microenvironment and drives immune ...
Fernanda V. Cabral +7 more
wiley +1 more source
Analytical solutions for macroscopic elastic moduli and thermal expansion coefficient of composite materials containing coated fillers oriented randomly based on the double inclusion method. [PDF]
Ono H.
europepmc +1 more source
Engineering Oncolytic Virus‐Armed Macrophages for Enhanced Cancer Immunotherapy
ZIFOA‐M is engineered by conjugating oncolytic adenovirus‐loaded ZIF‐8 nanoparticles onto macrophage surfaces via bioorthogonal chemistry. Upon tumor infiltration, the platform releases OA to downregulate CD47/CD24 on tumor cells, restoring macrophage phagocytosis.
Jilong Wang +10 more
wiley +1 more source
Quantifying Trace Metals in Gunflint Microfossils by 3D Correlative X-ray Nanoimaging. [PDF]
Lemelle L +15 more
europepmc +1 more source
NET‐DNA is enriched during early endometriotic lesion establishment and drives anoikis resistance by promoting an ANXA2–TMEM215–BiP axis. This pathway strengthens ER–mitochondria contacts, enhances PINK1/Parkin‐associated mitophagy, preserves mitochondrial homeostasis, and supports ectopic stromal cell survival, thereby facilitating lesion persistence ...
Honglin Wang +12 more
wiley +1 more source
Neural network for predicting ship magnetic signatures at arbitrary depths and courses: a comparison with the multi-dipole model. [PDF]
Zielonacki K, Tarnawski J, Woloszyn M.
europepmc +1 more source
Fit-for-purpose conformal mapping for sustainable land administration in war-ravaged Syria. [PDF]
Habib M.
europepmc +1 more source
Organoid Brain‐Machine‐Interface Devices for Central Nervous System Repair
We envision organoid brain‐machine‐interface (Organoid‐BMI) devices as new biohybrid bidirectional communication pathways to connect the human CNS and the external world for personalized CNS repair and regeneration. ABSTRACT Central nervous system (CNS) repair and regeneration suffer from tremendous clinical challenges due to current limitations in ...
Yantao Xing +10 more
wiley +1 more source
Entropy generation and regression analysis of unsteady Carreau ternary hybrid nanofluid flow with electromagnetic and thermal influences. [PDF]
Sindhu T, Jagadeeshkumar K.
europepmc +1 more source
Quantifying Nanoparticle Layer Topography: Theoretical Modeling and Atomic Force Microscopy Investigations. [PDF]
Adamczyk Z, Sadowska M, Nattich-Rak M.
europepmc +1 more source

