Results 81 to 90 of about 7,633,646 (255)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Voltage dependence of proton pumping by bacteriorhodopsin mutants with altered lifetime of the m intermediate [PDF]

, 2013
The light-driven proton pump bacteriorhodopsin (BR) from Halobacterium salinarum is tightly regulated by the [H+] gradient and transmembrane potential.
Friedrich, Thomas, Éva Lörinczi, Sven Geibel, Thomas Friedrich, Geibel, Sven, Bamberg, Ernst, Lörinczi, Èva, Ernst Bamberg, Lörinczi Èva, Friedrich, T., Bamberg Ernst, Geibel, S., Friedrich Thomas, Geibel Sven, Bamberg, E., Lörinczi, E.   +15 more
core   +2 more sources

Improved Low Voltage Ride-Through Capability of DFIG with ESO Controller under Unbalanced Network Conditions

Majlesi Journal of Electrical Engineering
Under unbalanced grid condition, in a Doubly-Fed Induction Generator (DFIG), voltage, current, and flux of the stator become asymmetric. Therefore, active-reactive power and torque will be oscillating.
Ali Akbar Vali, Seyed Mohammad Hassan Hosseni, Javad Olamaei   +2 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

SINGLE SWITCH BUCK BOOST CONVERTER EXTENDED OUTPUT VOLTAGE DENGAN PID SEBAGAI PENGENDALI TEGANGAN KELUARAN

, 2020
Single switch buck-boost converter extended output voltage adalah pengembangan dari buck-boost converter konvensional dengan gain tegangan yang lebih besar.
Wibawa, Unggul, Ardhenta, Lunde, Mardiana, Eka   +2 more
core  

A high-efficiency non-isolated bidirectional converter for power exchange between PV array and battery

Scientific Reports
This paper proposes a high-efficiency non-isolated bidirectional DC-DC converter for power exchange between a photovoltaic (PV) array and a battery energy storage system.
Negin Shahidi, Ebrahim Salary
doaj   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Transient instability identification method of power system based on power response trajectory

International Journal of Electrical Power & Energy Systems
The identification of transient instability is essential for power system operation, yet existing methods demand stringent measurement conditions and complex monitoring of generator power angles and angular velocities. Hence, a novel method for transient
Jian Liu, Kaijian Wei, Sheng Lin, Zhengyou He   +3 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source