Results 91 to 100 of about 3,169,150 (273)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Neglected Harms: Health Workers Organizing for Accountability in Tigray [PDF]

Health and Human Rights
Among the many crimes committed during the Tigray war from 2020 to 2022, the systematic destruction of health care has been extensively documented and contributed to the suffering and death of hundreds of thousands of civilians.
Dawit Kassa, Zazie Huml, Bram Wispelwey
doaj  

Distribution of Two Mating-Type Idiomorphs in Commercially Cultivated Morchella sextelata Unveiling Unique Life Cycle of Morels

Horticulturae
The outdoor cultivation of true morels has been successfully commercialized in China in recent years. However, unstable yields make it a high-risk business.
Jingting Wang, Dezheng Zhu, Xiaobo Li, Xia Gao, Yan Zhang, Meixiu Liu, Weidong Lu, Lili Xu, Hao Yu, Xiuqing Yang   +9 more
doaj   +1 more source

Beyond Rehabilitation of Acuity, Ocular Alignment, and Binocularity in Infantile Strabismus

Frontiers in Systems Neuroscience, 2018
Infantile strabismus impairs the perception of all attributes of the visual scene. High spatial frequency components are no longer visible, leading to amblyopia. Binocularity is altered, leading to the loss of stereopsis.
Chantal Milleret, Emmanuel Bui Quoc
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Prediction of Scour Hole Dimension Downstream of Siphon Spillway Under Submerged Condition [PDF]

مهندسی منابع آب, 2020
In this research work, besides analyzing the scour hole at the downstream of the siphon spillway physical model, some equations have been presented to predict scour hole developing.
mehdi fuladipanah, reza jafarinia
doaj  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Extended admissibility

Theoretical Computer Science, 2002
We give a new definition of admissible representations which allows to handle also non countably-based topological spaces in the framework of Type-2 Theory of Effectivity. We prove that admissible representations \(\delta_{X},\delta_{Y}\) of topological spaces \(X,Y\) have the desirable property that every partial function \(f\subseteq X\rightarrow Y\)
openaire   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Who continues to work after retirement age?

BMC Public Health
Background Demographic changes in all industrialized countries have led to a keen interest in extending working lives for older workers. To achieve this goal, it is essential to understand the patterns of retirement and specifically what characterizes ...
Sarah Zaccagni, Anna Munk Sigsgaard, Karsten Vrangbaek, Laura Pirhonen Noermark   +3 more
doaj   +1 more source