Results 81 to 90 of about 507,152 (254)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Strongly Uniform Extending Modules [PDF]
, 2018 In this paper, we introduced and studied the concept of strongly uniform extending modules, An R-module M is called strongly uniform extending (or M has (1-SC1) condition) if every uniform submodule of M is essential in a stable (fully invariant) direct ...
Saad Abdulkadhim Al-Saadi +1 more
core +1 more source
Proceedings of the American Mathematical Society, 1981 Amplifying modestly on recent work of R. W. Henrichs, we indicate that, while the impossibility of extending a continuous character ψ
openaire +2 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Extending Knowledge in Practice: Primary ICT by John Duffty
, 2007 book review of: Extending Knowledge in Practice: Primary ICT. Preparing teachers to make effective use of technology to enhance learning presents continuing challenges around the world.
Albion, Peter
core +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
A Genome Scaffold Algorithm for Extending Repetitive and Nonrepetitive Contigs [PDF]
, 2017 The next generation sequencing platform produces massive short reads data. It is needed to assemble these short reads for further analysis. Unfortunately, gene assembly algorithm is still faced by a variety of complex challenges, especially for ...
Xiaoli Zhang +4 more
core +1 more source
Extending the Capillary Tube of a Propane Air-conditioner to Reduce the Refrigerant Charge [PDF]
, 2017 Hydrocarbon refrigerants are employed to replace synthetic refrigerants due totheir low global warming and ozone depletion potentials; however, these refrigerants are flammable; therefore, their mass in the system should be minimized to reduce the ...
Ahmad Sharifian +3 more
core +1 more source
Proceedings of the American Mathematical Society, 1989 Consider a Polish topological group G G acting via
openaire +2 more sources