Results 91 to 100 of about 1,140,794 (311)
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Developmental Potential of Abnormally Fertilized Oocytes and the Associated Clinical Outcomes
Frontiers in Physiology, 2020 This study aims to investigate the embryo development potential of extending the culture of abnormally fertilized zygotes with no pronuclear (0PN), monopronuclear (1PN), and poor-quality day 3 embryos and to determine the associated clinical outcomes ...
Xiao Chen +4 more
doaj +1 more source
Extending working life in Belgium. CEPS Working Document No. 386, 22 November 2013 [PDF]
, 2013 This report aims at understanding how persons aged 50 years and older are and can be integrated into the working society in Belgium. We are interested in how people in this age group can be induced to engage in various forms of employment and lifelong ...
Marttellucci, Elisa +2 more
core
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
VIEW Journal of European Television History and Culture, 2015 Beyond their roles of broadcasting programmed content into the homes of people around the country, Britain’s British Broadcasting Corporation and Independent Television stations delivered additional content via the home television set.
Gazzard, Alison
doaj +1 more source
Multiple flow direction algorithm based on extending neighborhood terrain [PDF]
, 2013 Flow direction algorithm is an important research area in hydrological analysis. In this paper, a novel flow direction algorithm with varied trend of extending neighborhood terrain is introduced, which is based on the basic principle of multiple flow ...
Chen XL(陈雪莲) +2 more
core
Extending the ice core record beyond half a million years [PDF]
, 2002 Ice cores have been a crucial source of information about past changes in the climate and atmosphere. The Vostok ice core from Antarctica has provided key global change data sets extending 400,000 years in the past [Petit et al., 1999], while Japanese ...
The EPICA Dome C 2001-02 Science and Drilling Teams
core +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Live Longer, Work Longer: Making It Happen in the Labor Market [PDF]
Financial Theory and Practice, 2008 An aging population and the corresponding shrinkage of the labor force will create a significant drag on economic growth and may jeopardize the economic well-being of some of the elderly. Thus working longer is an imperative – but extending working lives
Milan Vodopivec, Primož Dolenc
doaj
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source