Results 131 to 140 of about 915,178 (269)
Elliptic arrangements of complex multiplication type
Forum of Mathematics, SigmaWe provide a natural definition of an elliptic arrangement, extending the classical framework to an elliptic curve $\mathcal {E}$ with complex multiplication.
Luca Moci +3 more
doaj +1 more source
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
SSEP Modules and Trivial Extensions
AmesiaIn this paper, we study the behavior of modules possessing the Summand Sum Essential Property (SSEP) in the context of trivial extensions of rings.
Eren Doğan, Mustafa Alkan
doaj +1 more source
A CHARACTERIZATION OF GOLDIE EXTENDING MODULES OVER DEDEKIND DOMAINS
, 2011 In this paper, we characterize [Formula: see text]-extending (Goldie extending) modules over Dedekind domains and we use the [Formula: see text]-extending condition to characterize the modules over a principal ideal domain whose pure submodules are ...
ADNAN TERCAN +5 more
core +1 more source
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
MC21 v.10 – coupled-radiation Monte Carlo transport solver with support for multiphysics simulations
EPJ Nuclear Sciences & TechnologiesOver the past decade, the development of the MC21 Monte Carlo radiation transport solver has focused on extending the functionality of the code beyond static calculations of reactivity and reaction rate distributions, as well as improving accuracy ...
Griesheimer David P. +7 more
doaj +1 more source
Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
Molecular Oncology, EarlyView.We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source